Measurement of Anti-dsDNA by Both CLIFT & ELISA

NCT03303508 | Unknown

• 1 other identifier: CLIFT & ELISA
• Study Type: interventional
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

detection of anti-ds DNA in patients with rheumatic diseases by two methodes : immunofluorescence \& ELISA

Conditions

Antiphospholipid Syndrome

Outcome Measures

Primary Outcomes (1)

• Comparison Between Immunofluorescence and Enzyme Immunoassay

  Verfication of the anti-dsDNA examination methods used in the Laboratory of Clinical Immunology, Assiut University Hospital.

  one year

Secondary Outcomes (1)

• Detection of Anti-Double Stranded Deoxyribonucleic Acid Antibodies in Autoimmune Rheumatic Diseases

  one year

Study Arms (1)

anti-ds DNA

OTHER

anti-ds DNA

Diagnostic Test: anti-ds DNA

Interventions

anti-ds DNA DIAGNOSTIC_TEST

venous blood samples

Also known as: venous blood samples

anti-ds DNA

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• The study will include patients with suspected diagnosis of autoimmune rheumatic diseases referred to the Laboratory of Clinical Immunology, Clinical Pathology Department, Assiut University Hospital for anti-dsDNA test. Patients will be recruited into the study within period of one year.
• Also, apparently healthy subjects (at least 25 subjects; according to international method verification guidelines) will be included as a control group

You may not qualify if:

• Subjects refused to be included in the study. Patients without a definite diagnosis of autoimmune rheumatic disease

Sponsors & Collaborators

• Assiut University: lead

Related Publications (1)

• Bai Y, Tong Y, Liu Y, Hu H. Self-dsDNA in the pathogenesis of systemic lupus erythematosus. Clin Exp Immunol. 2018 Jan;191(1):1-10. doi: 10.1111/cei.13041. Epub 2017 Sep 15.

  PMID: 28836661 BACKGROUND

MeSH Terms

Conditions

Antiphospholipid Syndrome

Condition Hierarchy (Ancestors)

Autoimmune Diseases; Immune System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Detection of Anti-Double Stranded Deoxyribonucleic Acid Antibodies in Autoimmune Rheumatic Diseases

Model Details: The study will include patients with suspected diagnosis of autoimmune rheumatic diseases referred to the Laboratory of Clinical Immunology, Clinical Pathology Department, Assiut University Hospital for anti-dsDNA test. Patients will be recruited into the study within period of one year. Also, apparently healthy subjects (at least 25 subjects; according to international method verification guidelines) will be included as a control group.

Study Record Dates

• First Submitted: September 27, 2017
• First Posted: October 6, 2017
• Study Start: September 1, 2018
• Primary Completion: September 1, 2019
• Study Completion: October 1, 2019
• Last Updated: October 6, 2017

Record last verified: 2017-09