NCT03300011

Brief Summary

Chronic total occlusions (CTO) are encountered in almost one-fourth of patients undergoing coronary angiography. The presence of an untreated CTO has been related to adverse clinical prognosis, both in stable angina and acute myocardial infarction, and is often associated with persistent symptomatic angina. Depending on their symptomatic and functional status as well as anatomical complexity, CTO can be treated by optimal medical therapy only or therapy combined with coronary revascularization. This study designed to evaluate the safety and efficacy of coronary chronic total occlusion PCI by ultrasonic cardiogram.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2016

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

September 27, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 3, 2017

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2018

Completed
Last Updated

October 3, 2017

Status Verified

September 1, 2017

Enrollment Period

2 years

First QC Date

September 27, 2017

Last Update Submit

October 2, 2017

Conditions

Keywords

ultrasonicchronic total occlusionheart function

Outcome Measures

Primary Outcomes (2)

  • cardiac death,

    patients with CTO postoperative sudden death cause for acute myocardial infarction or severe arrhythmia

    postoperation 1year

  • MACE

    recurrent severe angina, revascularization

    postoperation 1year

Study Arms (3)

recanalisation CTO lesion successful

EXPERIMENTAL

Patients with CTO lesion performed PCI strategy and successfully recanalisation the CTO lesion with implanted stents .

Device: stent

recanalisation CTO lesion failure

NO INTERVENTION

Patients with CTO lesion performed PCI strategy and failure recanalisation the CTO lesion with PCI wire and balloon..

OMT

NO INTERVENTION

Patients with CTO lesion optimal medicine treatment without PCI

Interventions

stentDEVICE

PTCA or PCI

Also known as: Balloon
recanalisation CTO lesion successful

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • coronary artery of chronic total occlusion

You may not qualify if:

  • ACS in 3months; once PCI or CABG; AF

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongda Hospital

Nanjing, Jiangsu, 210009, China

RECRUITING

MeSH Terms

Interventions

Stents

Intervention Hierarchy (Ancestors)

Prostheses and ImplantsEquipment and Supplies

Central Study Contacts

Chen Lijuan, Ph.D

CONTACT

Ma Genshan, Ph.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
masking for Ultrasonic Cardiogram investigator
Purpose
OTHER
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

September 27, 2017

First Posted

October 3, 2017

Study Start

October 1, 2016

Primary Completion

October 1, 2018

Study Completion

October 1, 2018

Last Updated

October 3, 2017

Record last verified: 2017-09

Data Sharing

IPD Sharing
Will not share

Locations