NCT03298737

Brief Summary

The purpose of this study is to provide information about how the brain processes sensory inputs using visual stimuli throughout various psychophysical experiments.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
4mo left

Started Oct 2017

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
enrolling by invitation

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress96%
Oct 2017Sep 2026

First Submitted

Initial submission to the registry

September 20, 2017

Completed
12 days until next milestone

First Posted

Study publicly available on registry

October 2, 2017

Completed
24 days until next milestone

Study Start

First participant enrolled

October 26, 2017

Completed
8.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

October 10, 2025

Status Verified

October 1, 2025

Enrollment Period

8.9 years

First QC Date

September 20, 2017

Last Update Submit

October 8, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pursuit eye movements to peripheral moving stimuli

    Pursuit eye movements are smooth eye movements with slow velocities (\< 15 degs/sec) that track the motion of visual stimuli when they are at the center of the visual field (Madelain and Krauzlis, J. of Vision, 2003). Here we will test the prediction that pursuit eye movements begin to track the motion of the stimulus located peripherally as an eye movement moves to the stimulus. The null hypothesis is that there will be no effect of the peripheral stimulus motion on the pursuit eye movements. We will measure eye movements using an infra-red eye tracker (Arrington, Inc) from 500 or more trials collected in each session. The distribution of pursuit eye movements will be computed for each subject to evaluate if there is significant pursuit along the direction of stimulus motion around the time of the saccade. The mean per participant will be determined and group effects evaluated.

    baseline

Study Arms (1)

Correct to normal vision population

Behavioral: Covert Spatial Attention

Interventions

During behavioral sessions, subjects will sit in a dark room and view a video monitor placed at the minimum of 57 cm distance away from the subject. Staff will be present throughout all the testing to assist the subject and monitor equipment that is used for tracking their eye position. Subjects will be asked to maintain their heads in a stable position of rest in order to insure accurate tracking of their eye position. To stabilize their head, subjects will either use a "chin rest" in which they position their chin on a soft pad mounted in front of a video screen, or they may use a "bite bar."

Correct to normal vision population

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Healthy participants age 18-65 with corrected to normal vision

You may qualify if:

  • Age between 18-65
  • Corrected-to-normal vision
  • No known diagnosis of visual or auditory disorder or impairment

You may not qualify if:

  • Does not have corrected-to-normal vision
  • Unable to understand and follow the instructions given of the study
  • Known diagnosis of visual or auditory disorder or impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Brain and Cognitive Sciences, University of Rochester

Rochester, New York, 14604, United States

Location

Related Publications (1)

  • Madelain L, Krauzlis RJ. Pursuit of the ineffable: perceptual and motor reversals during the tracking of apparent motion. J Vis. 2003 Nov 18;3(11):642-53. doi: 10.1167/3.11.1.

    PMID: 14765950BACKGROUND

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

September 20, 2017

First Posted

October 2, 2017

Study Start

October 26, 2017

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

October 10, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Locations