NCT03286439

Brief Summary

This study aims to investigate the in-hospital care as well as the cognitive status, quality of life, physical function and risk of anxiety and depression, sleep disorders and drug use in a Danish cohort of both medical and surgical patients with acute critical illness without admittance to ICU (Intensive Care Unit) treatment, at three and twelve months after hospital discharge.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
101

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2017

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 14, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 18, 2017

Completed
2 months until next milestone

Study Start

First participant enrolled

November 13, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 6, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 6, 2018

Completed
Last Updated

September 25, 2018

Status Verified

September 1, 2018

Enrollment Period

8 months

First QC Date

September 14, 2017

Last Update Submit

September 23, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cognitive function

    Cognitive Function measured by The Repeatable Battery for The Assesment of Neuropsychological Status (RBANS)

    3 months after discharge

Secondary Outcomes (27)

  • Cognitive function after one year

    12 months after discharge

  • Rehabilitation after 3 months

    3 months after discharge

  • Self-reported health related quality of life

    3 months after discharge

  • Self-reported health related quality of life

    12 months after discharge

  • Objective assessment of physical function

    3 months after discharge

  • +22 more secondary outcomes

Interventions

The investigators will offer the patients a follow up visit 3 and 12 months after discharge from the hospital.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The study population consists of critically ill patients that have been admitted to surgical or Medical departement.

You may qualify if:

  • Patients \> 18 years of age
  • Admitted to surgical or medical department \> 3 days
  • Admitted with one of the following diagnoses:
  • Pneumonia
  • Heart failure
  • Pulmonary embolism
  • Acute myocardial infarction
  • Pyelonephritis
  • Patients undergoing non-elective open or laparoscopic abdominal surgery (not including elective procedures, diseases of the appendix, diseases of the gallbladder, liver, spleen, kidney, pancreas and emergency hernia surgery without bowel resection)

You may not qualify if:

  • Permanently incompetent patients not able to consent
  • Not able to speak and understand Danish
  • Discharged from the hospital for terminal care
  • Patients transferred to another hospital during the stay
  • Patients living outside the Region of Zealand
  • Patients admitted under duress or actively psychotic
  • Patients that are blind or severely visually impaired.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zealand University Hospital

Køge, 4600, Denmark

Location

MeSH Terms

Conditions

Cognition Disorders

Condition Hierarchy (Ancestors)

Neurocognitive DisordersMental Disorders

Study Officials

  • Stine Estrup, MD

    Stine Estrup

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

September 14, 2017

First Posted

September 18, 2017

Study Start

November 13, 2017

Primary Completion

July 6, 2018

Study Completion

July 6, 2018

Last Updated

September 25, 2018

Record last verified: 2018-09

Data Sharing

IPD Sharing
Will not share

Locations