NCT03286309

Brief Summary

The soft robotic system could provide objective and quantifiable measures of subject performance. By combining voluntary motor intention and the robotic hand technology, the system will facilitate the recovery process of stroke patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Apr 2018

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 15, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 18, 2017

Completed
7 months until next milestone

Study Start

First participant enrolled

April 12, 2018

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2022

Completed
Last Updated

May 23, 2022

Status Verified

May 1, 2022

Enrollment Period

4.2 years

First QC Date

September 15, 2017

Last Update Submit

May 17, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Upper limb Fugl Meyer Assessment

    3-month follow up

Secondary Outcomes (4)

  • Action Research Arm Test

    3-month follow up

  • Modified Ashworth Scale

    3-month follow up

  • Box and Block Test

    3-month follow up

  • Max Voluntary Grip Force

    3-month follow up

Study Arms (2)

EMG-driven soft robot hand

EXPERIMENTAL

subjects will receive EMG-driven soft robot hand system.

Device: soft robot hand system

sham group

PLACEBO COMPARATOR

subjects will receive passive pre-programmed soft robot hand system.

Device: soft robot hand system

Interventions

subjects will wear the soft robot hand system and receive 60 minutes (including preparation time) hand exercise.

EMG-driven soft robot handsham group

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • at chronic stage (6 months after the onset of stroke) with a pure unilateral motor paresis after a stroke (ischemic or hemorrhagic);
  • sufficient cognition to follow simple instructions as well as understand the content and purpose of the study;
  • able to sit up for 45 minutes (with or without assistance).

You may not qualify if:

  • Patients with severe dysphasia (either expressive or comprehensive) with inadequate communication;
  • any additional medical or psychological condition affecting their ability to comply with the study protocol;
  • history of other neurological disease, psychiatric disorder, including alcoholism and substance abuse.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Biomedical Engineering, The Chinese University of Hong Kong

Shatin, Hong Kong

RECRUITING

Related Publications (1)

  • Shi XQ, Ti CE, Lu HY, Hu CP, Xie DS, Yuan K, Heung HL, Leung TW, Li Z, Tong RK. Task-Oriented Training by a Personalized Electromyography-Driven Soft Robotic Hand in Chronic Stroke: A Randomized Controlled Trial. Neurorehabil Neural Repair. 2024 Aug;38(8):595-606. doi: 10.1177/15459683241257519. Epub 2024 May 29.

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Raymond Kai-yu Tong, PhD

    Department of Biomedical Engineering, CUHK

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Raymond Kai-yu Tong, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

September 15, 2017

First Posted

September 18, 2017

Study Start

April 12, 2018

Primary Completion

July 1, 2022

Study Completion

July 1, 2022

Last Updated

May 23, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

Locations