NCT03285516

Brief Summary

The primary aim of the current proposal is to test the acceptability and feasibility of a group-based transdiagnostic treatment, termed Safety Aid Reduction Treatment (START), delivered to rural Veterans. The anticipated results of the proposed study include: 1) START will be both acceptable and feasible to Veterans and mental health care providers, alike and 2) START will lead to meaningful reductions in symptoms of anxiety and depression.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 12, 2017

Completed
2 months until next milestone

First Posted

Study publicly available on registry

September 18, 2017

Completed
7 months until next milestone

Study Start

First participant enrolled

April 16, 2018

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 2, 2019

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2019

Completed
Last Updated

March 2, 2020

Status Verified

February 1, 2020

Enrollment Period

12 months

First QC Date

July 12, 2017

Last Update Submit

February 27, 2020

Conditions

Keywords

transdiagnostic treatmentemotional disordersveteransrural

Outcome Measures

Primary Outcomes (1)

  • START Qualitative Treatment Questionnaire

    The START Qualitative Treatment Questionnaire is a brief, structured short-answer qualitative questionnaire that was developed by the research team to assess Veterans experience with the START protocol.

    8 weeks

Secondary Outcomes (4)

  • Overall Anxiety Severity and Impairment Scale (OASIS)

    Baseline and 8 weeks and 12 weeks

  • Overall Depression Severity and Impairment Scale (ODSIS)

    Baseline and 8 weeks and 12 weeks

  • Safety Behavior Assessment Form (SBAF)

    Baseline and 8 weeks and 12 weeks

  • Work and Social Adjustment Scale (WSAS)

    Baseline and 8 weeks and 12 weeks

Study Arms (1)

START

EXPERIMENTAL

The Safety Aid Reduction Treatment (START) protocol will consist of eight group sessions, delivered once weekly, lasting approximately one hour in duration. START will be delivered in-person by the PI and group co-leader.

Behavioral: Safety Aid Reduction Treatment

Interventions

START includes many of the key elements found in empirically supported treatments for emotional disorders including a) psychoeducation regarding the nature of distress and b) exposure to internal sensations and external situations that are connected to one's distress response via identification and reduction in safety aids. Safety aids discussed in the current protocol include cognitive avoidance, situational avoidance, checking behaviors, reassurance seeking, avoidance of bodily sensations, companions, and use of alcohol and other substances.

START

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years of age and older
  • Veterans must be diagnosed with an emotional disorder (e.g., anxiety disorder, obsessive-compulsive and related disorder, trauma-and stressor-related disorder, depressive disorder).
  • And be primarily served at a CBOC location.

You may not qualify if:

  • \< 18 years of age
  • Currently dependent upon substances and in need of detoxification
  • Evidence of active psychosis
  • Acutely suicidal or homicidal
  • Uncontrolled bipolar disorder (e.g., not stable on medications)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southeast Louisiana Veterans Health Care System

New Orleans, Louisiana, 70112, United States

Location

Related Publications (4)

  • Veterans Health Administration Office of Rural Health. ORH Fact Sheet. 2014; Available from: http://www.ruralhealth.va.gov.

    BACKGROUND
  • Allen, L.B., R.K. McHugh, and D.H. Barlow, Emotional disorders: A unified protocol. 2008.

    BACKGROUND
  • Schmidt NB, Buckner JD, Pusser A, Woolaway-Bickel K, Preston JL, Norr A. Randomized controlled trial of false safety behavior elimination therapy: a unified cognitive behavioral treatment for anxiety psychopathology. Behav Ther. 2012 Sep;43(3):518-32. doi: 10.1016/j.beth.2012.02.004. Epub 2012 Mar 9.

    PMID: 22697441BACKGROUND
  • Riccardi CJ, Korte KJ, Schmidt NB. False Safety Behavior Elimination Therapy: A randomized study of a brief individual transdiagnostic treatment for anxiety disorders. J Anxiety Disord. 2017 Mar;46:35-45. doi: 10.1016/j.janxdis.2016.06.003. Epub 2016 Jun 18.

    PMID: 27397584BACKGROUND

Study Officials

  • Amanda M. Raines, Ph.D.

    Southeast Louisiana Veterans Health Care System

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SINGLE GROUP
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Clinical Psychologist

Study Record Dates

First Submitted

July 12, 2017

First Posted

September 18, 2017

Study Start

April 16, 2018

Primary Completion

April 2, 2019

Study Completion

April 30, 2019

Last Updated

March 2, 2020

Record last verified: 2020-02

Data Sharing

IPD Sharing
Will not share

Data sets underlying this project will not be shared outside the VA, except as required under the Freedom of Information Act (FOIA), for a number of reasons. First, data will be used by the research team to answer additional research questions. Further, veterans may be hesitant to participate in research in which the data will be shared outside the VA and this may act as a barrier to participation and/or benefit from treatment.

Locations