Review and Assessment of Network Meta-analyses for Knowledge Uptake Study

NCT03283592 | Withdrawn

• 1 other identifier: 17-0107
• Study Type: interventional
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

This randomized controlled trial will assess the interpretability of the rank-heat plot for presenting the results of network meta-analysis in comparison to SUCRA (surface under the cumulative ranking) plots which are suggested to present one of the best ranking statistics.

Conditions

Clinical Decision-making

Outcome Measures

Primary Outcomes (1)

• Proportion of participants who appropriately define the clinical "bottom line." Participants' answers will be independently evaluated by two investigators for agreement with an expert panel's recommendation.

  during experiment via single session, <1 hour survey

Secondary Outcomes (3)

• Proportion of participants who accurately apply the evidence to the provided clinical scenario.

  during experiment via single session, <1 hour survey

• Completeness of survey data evaluated by two independent investigators

  Immediate post-experiment

• Time taken to complete survey

  Immediate post-experiment

Study Arms (2)

Rank-Heat Plot

EXPERIMENTAL

The intervention group will receive an online survey to evaluate their interpretation of the results from the NMA with a rank-heat plot including results from 2 outcomes that were selected by our knowledge users (#injurious falls, #fractures).

Other: Rank-Heat Plot

SUCRA (surface under the cumulative ranking) Plot

ACTIVE COMPARATOR

The control group will receive an online survey to evaluate their interpretation of the results from the NMA with the SUCRA plots including results from the same 2 outcomes that will be presented to the intervention group (i.e., #injurious falls, #fractures).

Other: SUCRA Plot

Interventions

Rank-Heat Plot OTHER

provides a visual presentation of treatment hierarchy across multiple outcomes

Rank-Heat Plot

SUCRA Plot OTHER

provides a visual presentation of treatment ranking for a single outcome.

SUCRA (surface under the cumulative ranking) Plot

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Clinicians must be accredited to practice in Canada and working (full- or part-time) as a family physician or general internist.

You may not qualify if:

• Unable to read and understand English;
• No access to the internet;
• Read, co-authored or peer-reviewed the study: "Quality Improvement strategies to Prevent Falls in the Elderly: A systematic review and network meta-analysis" (manuscript in preparation).

Sponsors & Collaborators

• Unity Health Toronto: lead

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Masking Details: Single blind (outcome assessor)
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 2-arm, parallel assignment

Study Record Dates

• First Submitted: September 11, 2017
• First Posted: September 14, 2017
• Study Start: July 1, 2019
• Primary Completion: January 1, 2021
• Study Completion: January 1, 2021
• Last Updated: April 4, 2019

Record last verified: 2019-04