NCT03283501

Brief Summary

Evaluate incidence, clinical indications, and feasibility of PCI performed after TAVI.

Trial Health

47
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2017

Shorter than P25 for all trials

Geographic Reach
2 countries

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 20, 2017

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

September 4, 2017

Completed
10 days until next milestone

First Posted

Study publicly available on registry

September 14, 2017

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2017

Completed
Last Updated

September 14, 2017

Status Verified

September 1, 2017

Enrollment Period

9 months

First QC Date

September 4, 2017

Last Update Submit

September 12, 2017

Conditions

Keywords

TAVIPCI

Outcome Measures

Primary Outcomes (4)

  • Evaluate the incidence of PCI after TAVI

    Evaluate the incidence of PCI after TAVI

    up to 5 year after TAVI implantation

  • Evaluate the clinical indications for PCI after TAVI

    Clinical indication for PCI: stable angina; documented silent ischemia; acute coronary syndrome/non-ST elevation myocardial infarction; acute coronary syndrome/ST elevation myocardial infarction

    intraoperative

  • Evaluate the technical feasibility of PCI in patients with prior TAVI

    Successful target coronary vessel revascularization

    intraoperative

  • Evaluate in-hospital and long-term clinical outcomes in patients undergoing PCI after TAVI

    outcome defined as MACE (Major Adverse Coronary Event) a composite of Death, Myocardial Infarction, Target Lesion Failure

    up to 5 year after TAVI implantation

Interventions

Any patient undergoing PCI after TAVI, irrespective of clinical indications and irrespective of whether planned or not at the time of TAVI

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Any patient undergoing PCI after TAVI, irrespective of clinical indications and irrespective of whether planned or not at the time of TAVI

You may qualify if:

  • Any patient undergoing PCI after TAVI, irrespective of clinical indications and irrespective of whether planned or not at the time of TAVI

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Humanitas Research Hospital, Humanitas University

Rozzano, Milan, Italy

RECRUITING

Interventional Unit, San Luigi Gonzaga University Hospital, Orbassano, and Rivoli Hospital, Turin, Italy

Turin, 10100, Italy

RECRUITING

Hospital Clinico San Carlos

Madrid, Spain

RECRUITING

Related Publications (1)

  • Stefanini GG, Cerrato E, Pivato CA, Joner M, Testa L, Rheude T, Pilgrim T, Pavani M, Brouwer J, Lopez Otero D, Munoz Garcia E, Barbanti M, Biasco L, Varbella F, Reimers B, Jimenez Diaz VA, Leoncini M, Salido Tahoces ML, Ielasi A, de la Torre Hernandez JM, Mylotte D, Garot P, Chieffo A, Nombela-Franco L; REVIVAL Investigators. Unplanned Percutaneous Coronary Revascularization After TAVR: A Multicenter International Registry. JACC Cardiovasc Interv. 2021 Jan 25;14(2):198-207. doi: 10.1016/j.jcin.2020.10.031.

Related Links

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

September 4, 2017

First Posted

September 14, 2017

Study Start

April 20, 2017

Primary Completion

December 31, 2017

Study Completion

December 31, 2017

Last Updated

September 14, 2017

Record last verified: 2017-09

Locations