NCT03283358

Brief Summary

The overall aim of the study is to evaluate a nurse-led intervention (person-centered follow up and health promotion) program in comparison to standard follow up for patients treated with surgical or endovascular revascularization of Intermittent Claudication.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
213

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jun 2016

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 13, 2016

Completed
Same day until next milestone

Study Start

First participant enrolled

June 13, 2016

Completed
1.3 years until next milestone

First Posted

Study publicly available on registry

September 14, 2017

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2019

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2020

Completed
Last Updated

October 28, 2020

Status Verified

October 1, 2020

Enrollment Period

3.5 years

First QC Date

June 13, 2016

Last Update Submit

October 27, 2020

Conditions

Keywords

Prevention and control

Outcome Measures

Primary Outcomes (1)

  • Adherence to medication

    Adherence to medication (anticoagulant agents, antiplatelet agents and lipid-lowering agents) according to the Swedish Prescribed Drug Registry (PDR). dispensed anticoagulant agents, antiplatelet agents (ATC-register B01A) and lipid-lowering agents (ATC-register C10). Those participants who have fetched both medications for the second refill after treatment will be considered adherent.

    One year after surgical or endovascular treatment for Intermittent Claudication

Secondary Outcomes (1)

  • Risk for 10-year predicted coronary heart disease (CHD)

    One year after surgical or endovascular treatment for Intermittent Claudication

Other Outcomes (9)

  • Patient reported adherence to medication

    One year after surgical or endovascular treatment for Intermittent Claudication

  • Generic Health-related Quality of Life (HRQOL)

    One year after surgical or endovascular treatment for Intermittent Claudication

  • Condition specific Health-related Quality of Life (HRQOL)

    One year after surgical or endovascular treatment for Intermittent Claudication

  • +6 more other outcomes

Study Arms (2)

Person-centered follow up

EXPERIMENTAL

The intervention program is a person-centered health promotion program led by a nurse and consists of two telephone calls (15 minutes each) at two weeks and nine months after surgical treatment for Intermittent Claudication and three visits (45 - 60 min) at six weeks, six months and one year after treatment. The program includes a baseline assessment, an individual plan for self-care and educational information about Intermittent Claudication, received treatment and secondary prevention (medication and modifiable risk factors). The purpose is to enhance self-care in terms of adherence to medication and to recommended changes of lifestyle.

Behavioral: Person-centered follow up

Standard follow up

NO INTERVENTION

Standard follow-up consist of two follow up appointments á 20 minutes at four-six weeks and one year after surgical treatment of Intermittent Claudication. The patients meet a vascular surgeon at the first follow up and a vascular nurse or a surgeon at the second follow up visit.

Interventions

Person-centered follow up

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult patients who is scheduled for revascularization, through open and/or endovascular surgery for IC diagnosed according to Diagnosis Related Group (DRG) with I70.2 or I739B

You may not qualify if:

  • Patients not treated through surgery or revascularization
  • Patients diagnosed with dementia
  • Patients discharge to a nursery home,
  • Patients not accountable for administrating their own medications
  • Patients with a survival expectancy less than one year

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Department of Surgery, Unit of Vascular Surgery, Södersjukhuset

Stockholm, SE-11883, Sweden

Location

Karolinska University Hospital, Dept of Vascular Surgery

Stockholm, Sweden

Location

Related Publications (2)

  • Haile ST, Olsson M, Lindstrand R, Loof H, Linne A, Johansson UB, Joelsson-Alm E. Patient Reported Experiences of Receiving Person-Centred, Nurse-Led Follow-Up After Revascularisation for Intermittent Claudication: Secondary Analysis of a Randomised Controlled Trial. J Clin Nurs. 2025 Jul;34(7):3003-3016. doi: 10.1111/jocn.17762. Epub 2025 May 20.

  • Haile S, Linne A, Johansson UB, Joelsson-Alm E. Follow-up after surgical treatment for intermittent claudication (FASTIC): a study protocol for a multicentre randomised controlled clinical trial. BMC Nurs. 2020 Jun 4;19:45. doi: 10.1186/s12912-020-00437-7. eCollection 2020.

MeSH Terms

Conditions

Intermittent Claudication

Condition Hierarchy (Ancestors)

Peripheral Arterial DiseasePeripheral Vascular DiseasesVascular DiseasesCardiovascular DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Anneli Linné, MD, PhD

    Karolinska Institutet, Department of Clinical Science and Education, Södersjukhuset

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

June 13, 2016

First Posted

September 14, 2017

Study Start

June 13, 2016

Primary Completion

November 30, 2019

Study Completion

May 31, 2020

Last Updated

October 28, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations