A Survey on Blood Transfusions in Major Artrhoplasty Operations

NCT03282201 | Completed

• 1 other identifier: TransfusionArthroplasty
• Study Type: observational
• Target: 418
• Locations: 1 country
• Sites: 1

Brief Summary

The rate of hip, knee arthroplasties and their revision are increasing every year. The incidence of blood transfusion in these operations are reported 18%, 68%, and 39%, 67%, respectively. Blood transfusion is known to increase the risk of pulmonary, septic, wound and thromboembolic complications and is related to mortality. Restrictive transfusion protocols has cost-effective results in terms of reducing these complications, promoting early discharge and reduced frequency of re-admission. Within this context, we aimed to evaluate the transfusion practice in our hospital, define the transfusion indicators and compare the transfused and non transfused patients in terms of recovery.

Conditions

Arthropathy of Hip; Arthropathy of Knee

Outcome Measures

Primary Outcomes (2)

• Discharge time

  Discharge time from hospital

  Postoperative day 1-6 days

• TUG test

  Walking without help

  Postoperative day 1-2

Study Arms (2)

Transfused

Patients in whom blood transfusion is used

Other: Transfusion

Nontransfused

Patients in whom blood transfusion is not used

Interventions

Transfusion OTHER

Transfusion of red blood cells, fresh frozen plasma, platelets

Transfused

Eligibility Criteria

• Age: 18 Years - 95 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients undergoing major atrhroplasty

You may qualify if:

• Patients undergoing major atrhroplasty

You may not qualify if:

• Pediatric patients

Sponsors & Collaborators

• Diskapi Teaching and Research Hospital: lead

Study Sites (1)

Diskapi Yildirim Beyazit Teaching and Research Hospital

Ankara, 06110, Turkey (Türkiye)

Location

Related Publications (4)

• Poitras S, Wood KS, Savard J, Dervin GF, Beaule PE. Predicting early clinical function after hip or knee arthroplasty. Bone Joint Res. 2015 Sep;4(9):145-51. doi: 10.1302/2046-3758.49.2000417.

  PMID: 26336897 BACKGROUND

• Cram P, Vaughan-Sarrazin MS, Wolf B, Katz JN, Rosenthal GE. A comparison of total hip and knee replacement in specialty and general hospitals. J Bone Joint Surg Am. 2007 Aug;89(8):1675-84. doi: 10.2106/JBJS.F.00873.

  PMID: 17671004 BACKGROUND

• Engoren M, Mitchell E, Perring P, Sferra J. The effect of erythrocyte blood transfusions on survival after surgery for hip fracture. J Trauma. 2008 Dec;65(6):1411-5. doi: 10.1097/TA.0b013e318157d9f9.

  PMID: 19077635 RESULT

• Kotze A, Carter LA, Scally AJ. Effect of a patient blood management programme on preoperative anaemia, transfusion rate, and outcome after primary hip or knee arthroplasty: a quality improvement cycle. Br J Anaesth. 2012 Jun;108(6):943-52. doi: 10.1093/bja/aes135.

  PMID: 22593128 RESULT

MeSH Terms

Interventions

Blood Transfusion

Intervention Hierarchy (Ancestors)

Biological Therapy; Therapeutics

Study Officials

• Dilek Yazicioglu, Assoc Prof

  Ministry of Health

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Proffesor

Study Record Dates

• First Submitted: September 12, 2017
• First Posted: September 13, 2017
• Study Start: October 15, 2017
• Primary Completion: May 25, 2018
• Study Completion: June 20, 2018
• Last Updated: November 2, 2018

Record last verified: 2017-09

Locations

TU (1)