Fertility and Ovarian Reserve Function in the Patient With Inflammatory Bowel Disease
1 other identifier
interventional
80
1 country
1
Brief Summary
ECCO consensus, the fertility would decline in activity inflammatory bowel disease(IBD), because of anus lesions and pelvic abscess, or who underwent surgery, especially in patients with ileal pouch anal anastomosis (IPAA) storage.The study on fertility in inflammatory bowel disease were almost epidemiological investigation, the lack of objective evaluation of fertility, and controversial.This study will explore the fertility, ovarian reserve function and the pregnancy outcomes in patients with IBD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started May 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2017
CompletedFirst Submitted
Initial submission to the registry
August 13, 2017
CompletedFirst Posted
Study publicly available on registry
September 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2018
CompletedSeptember 1, 2017
August 1, 2017
1 year
August 13, 2017
August 29, 2017
Conditions
Outcome Measures
Primary Outcomes (4)
The AMH of IBD patients is lower than that of healthy women
AMH is used to assess ovarian reserve function
1 month
The E2 of IBD patients is lower than that of healthy women
E2 is used to assess ovarian reserve function
1 month
The FSH of IBD patients is lower than that of healthy women
FSH is used to assess ovarian reserve function
1 month
The AFC of IBD patients is lower than that of healthy women
AFC is used to assess ovarian reserve function
1 month
Study Arms (2)
IBD patients
EXPERIMENTALIBD patients, 17-40 years old, female
healthy control
OTHER17-40 years old , female, without any gynecological disease
Interventions
used to assess ovarian reserve parameters
Eligibility Criteria
You may qualify if:
- Inflammatory bowel disease
- years old
- female
You may not qualify if:
- in pregnancy or lactation
- a drug that has been or is being used known to affect ovarian function, such as cyclophosphamide
- reproductive system diseases unrelated to disease or treatment of inflammatory bowel disease, such as hysterectomy, pelvic radiotherapy after surgery, after ovariectomy, polycystic ovary syndrome, endometriosis, ovarian granulosa cell tumor
- other endocrine diseases, such as prolactin, hyperthyroidism, lead to endocrine disorders;
- malignant tumor
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
The Sixth Affiliated Hospital of Zhongshan University
Guangzhou, Guangdong, 510000, China
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Min Zhi, PHD
The Sixth Affiliated Hospital of Zhongshan University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Attending doctor
Study Record Dates
First Submitted
August 13, 2017
First Posted
September 1, 2017
Study Start
May 1, 2017
Primary Completion
May 1, 2018
Study Completion
August 1, 2018
Last Updated
September 1, 2017
Record last verified: 2017-08