NCT03268707

Brief Summary

A randomized, open, mono-centric pilot study to investigate the influence of an innovative telemetric smartphone application on re-hospitalization and quality of life after cryoballoon pulmonary vein isolation in patients with paroxysmal atrial fibrillation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 15, 2017

Completed
18 days until next milestone

First Submitted

Initial submission to the registry

August 2, 2017

Completed
29 days until next milestone

First Posted

Study publicly available on registry

August 31, 2017

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2020

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2021

Completed
Last Updated

June 18, 2019

Status Verified

June 1, 2019

Enrollment Period

3.5 years

First QC Date

August 2, 2017

Last Update Submit

June 15, 2019

Conditions

Keywords

Paroxysmal Atrial FibrillationPulmonary Vein IsolationTelemetry MonitoringCryoballoon ablation

Outcome Measures

Primary Outcomes (1)

  • Rehospitalization Recurrence of AF

    Rate of rehospitalization after cryoballoon pulmonary vein isolation in patients with paroxysmal atrial fibrillation, Recurrence of sustained atrial fibrillation (\>30 seconds) after atrial fibrillation ablation

    in 12 months follow up

Study Arms (2)

Conventional follow up

OTHER

Conventional follow up at physician practice

Other: Conventional follow up

Telemetric smartphone application

EXPERIMENTAL

Structured follow up with a telemetric smartphone application

Device: Telemetric smartphone application

Interventions

Structured follow up with a telemetric smartphone application

Telemetric smartphone application

Conventional follow up at physician practice

Conventional follow up

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \> 18 years
  • Written informed consent
  • symptomatic paroxysmal atrial fibrillation (at least two episodes within 3 months prior to ablation)
  • cryoballoon pulmonary vein isolation
  • possession of a compatible smartphone

You may not qualify if:

  • Age \< 18 years
  • persistent or permanent atrial fibrillation (AF)
  • prior catheter or surgical ablation of AF
  • pregnant females
  • contraindication for oral anticoagulation
  • manifest hyper-/hypothyroidism
  • no intention to cooperate
  • alcoholism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Asklepios St Georg

Hamburg, 20246, Germany

NOT YET RECRUITING

Universitätsklinikum Hamburg-Eppendorf

Hamburg, 20246, Germany

RECRUITING

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Christian Meyer, MD

    Universitaeres Herzzentrum Hamburg GmbH

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Melanie Gunawardene, MD

CONTACT

Christian Meyer, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 2, 2017

First Posted

August 31, 2017

Study Start

July 15, 2017

Primary Completion

December 31, 2020

Study Completion

June 30, 2021

Last Updated

June 18, 2019

Record last verified: 2019-06

Locations