Cardiac Magnetic Resonance for Asymptomatic Type 2 Diabetics With Cardiovascular High Risk (CATCH) - Pilot Study
CATCH
1 other identifier
interventional
63
1 country
1
Brief Summary
The aim of this study is to determine the prevalence of myocardial ischaemia in asymptomatic high risk type 2 diabetic patients using stress cardiac MR and how many stress cardiac MR examinations are false positive.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable diabetes-mellitus-type-2
Started Aug 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 10, 2017
CompletedFirst Submitted
Initial submission to the registry
August 24, 2017
CompletedFirst Posted
Study publicly available on registry
August 28, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 29, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
January 29, 2019
CompletedAugust 20, 2019
August 1, 2019
1.5 years
August 24, 2017
August 16, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Prevalence of myocardial ischaemia
1 year
Secondary Outcomes (3)
Prevalence of myocardial infarction
1 year
Clinical predictors of silent ischaemia
1 year
Major adverse cardiovascular events
1 year
Study Arms (1)
Stress Cardiac MR
EXPERIMENTALInterventions
Screening of asymptomatic of high risk type 2 diabetic mellitus patients with stress cardiac magnetic resonance
Eligibility Criteria
You may qualify if:
- Onset of type 2 diabetes at ≥30yrs old with no history of ketoacidosis
- yrs old
- Framingham Risk Score ≥20%
You may not qualify if:
- Angina pectoris or chest discomfort
- Stress test or coronary angiography within 2 years
- Previous myocardial infarction (MI)
- Previous coronary artery stenting or coronary artery bypass grafting
- Any clinical indication or contraindication for stress testing
- Any contraindication to stress CMR (eg. non-MRI compatible devices)
- Contraindication to gadolinium based contrast agent (eg. Renal impairment with an estimated glomerular filtration rate (GFR) \<30ml/min/1.73m2)
- Life expectancy \<2 years due to cancer or liver disease
- Contraindication to dual antiplatelet therapy
- Planned need for concomitant cardiac surgery
- Refusal or inability to sign an informed consent.
- Potential for non-compliance towards the requirements in the trial protocol
- Unable to cover the costs of percutaneous coronary intervention (PCI) whether through government subsidies, etc
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The University of Hong Konglead
- Radiological Society of North Americacollaborator
Study Sites (1)
The University of Hong Kong
Hong Kong, Hong Kong
Related Publications (1)
Ng MY, Zhou W, Vardhanabhuti V, Lee CH, Yu EYT, Wan EYF, Chan K, Yan AT, Ip TP, Yiu KH, Wintersperger BJ. Cardiac magnetic resonance for asymptomatic patients with type 2 diabetes and cardiovascular high risk (CATCH): a pilot study. Cardiovasc Diabetol. 2020 Mar 31;19(1):42. doi: 10.1186/s12933-020-01019-2.
PMID: 32234045DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 24, 2017
First Posted
August 28, 2017
Study Start
August 10, 2017
Primary Completion
January 29, 2019
Study Completion
January 29, 2019
Last Updated
August 20, 2019
Record last verified: 2019-08