New Genes in the Carcinogenesis of Colorectal Cancer
Investigating the Role of SPG20,STK31 Genes in the Carcinogenesis of Colorectal Cancer
1 other identifier
observational
62
0 countries
N/A
Brief Summary
Colo rectal cancer is one of the greatest ,mutual malignancies worldwide ,accounting for an estimated 1.3 million new cases and \>500,000 mortality ⁄ year . is the fourth leading cause of cancer-associated mortality worldwide with speedily ,cumulative ,occurrence rate in the worldwide
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Oct 2018
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
August 23, 2017
CompletedFirst Posted
Study publicly available on registry
August 25, 2017
CompletedStudy Start
First participant enrolled
October 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2019
CompletedJuly 26, 2018
July 1, 2018
11 months
August 23, 2017
July 24, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
detection of SPG20&STK31 genes
detection of SPG20\&STK31 genes and prediction future treatment for colo-rectal cancer
5 months
Study Arms (2)
patient with cancer
blood sample will be collected from patient before and after treatment (surgery or chemotherapy)
healthy people
blood sample will be collected for comparison
Interventions
Total genomic DNA will be extracted DNA extraction kit using a QIAamp DNA Blood Mini kit .Genetic analysis of both SPG20 \&STK31 by RTPCR.
Eligibility Criteria
patient between 35-65 who are newly diagnosed with colorectal cancer
You may qualify if:
- age between 35-65
- patient with colorectal cancer (at any stage)
- both sex included
You may not qualify if:
- pediatric patients
- patient with insufficient data
- cardiac patient
- pregnant women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Demonstrator of cancer biology
Study Record Dates
First Submitted
August 23, 2017
First Posted
August 25, 2017
Study Start
October 1, 2018
Primary Completion
September 1, 2019
Study Completion
September 1, 2019
Last Updated
July 26, 2018
Record last verified: 2018-07