Detection of Asymptomatic Venous Thrombosis in Gynecological Patients With Pelvic Masses

NCT03260270 | Unknown

• 1 other identifier: ASU
• Study Type: observational
• Target: 60
• Locations: 0 countries
• Sites: N/A

Brief Summary

Venous thromboembolism (VTE) is a serious preventable complication of gynecological surgery. High incidence of silent VTE before surgery seems attributable to the high incidence of VTE after surgery in ovarian cancer .so the aim of work is to detect silent venous thrombosis in gynecological patients suffering from pelvic masses using different imaging modalities .

Conditions

Silent; Thrombosis

Outcome Measures

Primary Outcomes (1)

• detection of asymptomatic venous thrombosis

  silent venous thrombosis in gynecological patients with pelvic masses

  one week before operation

Interventions

color doppler ultrasound DIAGNOSTIC_TEST

All patients are going to be examined by color Doppler ultrasound and the high risk patients are going to be examined by direct MDCT venography .

Also known as: direct MDCT venography

Eligibility Criteria

• Gender Eligibility Details: female patients in different age groups with gynecological masses detected by clinical examination and different imaging modalities.
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients admitted to Assiut University hospitals

You may qualify if:

• female patients in different age groups with gynecological masses detected by clinical examination and different imaging modalities.

You may not qualify if:

• patients with chronic kidney disease in case of contrast .
• patients complaining from hematological diseases that may cause venous thromboembolism .
• pregnant patients .
• patients already diagnosed with deep venous thrombosis.
• patients not fit for surgery.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (5)

• Ikeda M, Kan-no H, Hayashi M, Tsukada H, Shida M, Hirasawa T, Muramatsu T, Ogushi Y, Mikami M. Predicting perioperative venous thromboembolism in Japanese gynecological patients. PLoS One. 2014 Feb 26;9(2):e89206. doi: 10.1371/journal.pone.0089206. eCollection 2014.

  PMID: 24586595 BACKGROUND

• Qu H, Li Z, Zhai Z, Liu C, Wang S, Guo S, Zhang Z. Predicting of Venous Thromboembolism for Patients Undergoing Gynecological Surgery. Medicine (Baltimore). 2015 Sep;94(39):e1653. doi: 10.1097/MD.0000000000001653.

  PMID: 26426660 BACKGROUND

• Goodman LR, Stein PD, Matta F, Sostman HD, Wakefield TW, Woodard PK, Hull R, Yankelevitz DF, Beemath A. CT venography and compression sonography are diagnostically equivalent: data from PIOPED II. AJR Am J Roentgenol. 2007 Nov;189(5):1071-6. doi: 10.2214/AJR.07.2388.

  PMID: 17954642 BACKGROUND

• Kelly J, Rudd A, Lewis RR, Hunt BJ. Screening for subclinical deep-vein thrombosis. QJM. 2001 Oct;94(10):511-9. doi: 10.1093/qjmed/94.10.511. No abstract available.

  PMID: 11588209 BACKGROUND

• Satoh T, Oki A, Uno K, Sakurai M, Ochi H, Okada S, Minami R, Matsumoto K, Tanaka YO, Tsunoda H, Homma S, Yoshikawa H. High incidence of silent venous thromboembolism before treatment in ovarian cancer. Br J Cancer. 2007 Oct 22;97(8):1053-7. doi: 10.1038/sj.bjc.6603989. Epub 2007 Sep 25.

  PMID: 17895896 BACKGROUND

MeSH Terms

Conditions

Thrombosis

Condition Hierarchy (Ancestors)

Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Central Study Contacts

Dr. Gehan Sayed, assit prof

CONTACT

00201224417605; gehanseifeldein@yahoo.com

Dr.Omran Khodary, lecturer

CONTACT

00201117298484

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Week
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: August 22, 2017
• First Posted: August 24, 2017
• Study Start: September 1, 2017
• Primary Completion: September 1, 2020
• Study Completion: December 1, 2020
• Last Updated: August 24, 2017

Record last verified: 2017-08