NCT03260049

Brief Summary

The records of patients who were diagnosed with ARN between April 2010 and February 2017 were analyzed.A retrospective review of the treatment options and outcomes of the these patients was performed.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2012

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2012

Completed
4.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2017

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

August 21, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

August 24, 2017

Completed
Last Updated

August 24, 2017

Status Verified

August 1, 2017

Enrollment Period

4.8 years

First QC Date

August 21, 2017

Last Update Submit

August 21, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • visual acuity

    1 year

Secondary Outcomes (1)

  • retinal detachement

    1 year

Study Arms (3)

1

there was no retinal detachment (RD) at the first visit. The group 1 patients were treated with systemic antiviral medications, as well as with intravitreal antiviral injections

2

there was no RD at the first visit. The group 2 patients were treated with systemic antiviral medications and PPV plus silicone oil tamponade and intravitreal injection.

Procedure: pars plana vitrectomy

3

there was RD at the first visit. The group 3 patients were treated with systemic antiviral medications and PPV plus silicone oil tamponade and intravitreal injection

Procedure: pars plana vitrectomy

Interventions

pars plana vitrectomy

Also known as: systemic antiviral medications
23

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

ARN patients

You may qualify if:

  • ARN was diagnosed according to the American Uveitis Society Diagnostic Criteria (1994)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Retinal Necrosis Syndrome, Acute

Condition Hierarchy (Ancestors)

RetinitisRetinal DiseasesEye Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr.

Study Record Dates

First Submitted

August 21, 2017

First Posted

August 24, 2017

Study Start

April 1, 2012

Primary Completion

February 1, 2017

Study Completion

February 1, 2017

Last Updated

August 24, 2017

Record last verified: 2017-08

Data Sharing

IPD Sharing
Will not share