Acute Effects of Open and Closed Suction Systems in Mechanically Ventilated Patients
1 other identifier
interventional
71
0 countries
N/A
Brief Summary
Seventy-one patients in intensive care were randomized for initial treatment with open suction systems or closed suction systems in a cross-over design. Pulmonary and cardiovascular physiology was assessed immediately before and after three 10-second aspirations per suction. Were analyzed the effect of each suction system on physiologic parameters while adjusting for their respective values prior to suction.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Feb 2015
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 2, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 15, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
April 17, 2017
CompletedFirst Submitted
Initial submission to the registry
July 18, 2017
CompletedFirst Posted
Study publicly available on registry
August 21, 2017
CompletedAugust 21, 2017
August 1, 2017
1.4 years
July 18, 2017
August 16, 2017
Conditions
Outcome Measures
Primary Outcomes (2)
Improvements in Pulmonary parameters when comparing closed and open suction systems.
Assessment of Peak Pressure (cmH20) in both closed and open suction systems.
1 day
Improvements in Cardiovascular parameters when comparing Closed and open suction systems.
Assessment of Blood Pressure (mmHg) in both closed and open suction systems.
1 day
Study Arms (2)
Closed suction system
EXPERIMENTALPatients in mechanical ventilation were aspirated with closed suction system.
Open suction system
ACTIVE COMPARATORPatients in mechanical ventilation were aspirated with open suction system.
Interventions
In mechanically ventilated patients, intratracheal secretions were aspirated with closed suction systems to compare the pulmonary and cardiovascular parameters (Peak Pressure, Resistance, and Pressure Plateau, Heart Rate and Mean, Diastolic, and Systolic Pressures) with open suction system.
In mechanically ventilated patients, intratracheal secretions were aspirated with open suction systems to compare the pulmonary and cardiovascular parameters (Peak Pressure, Resistance, and Pressure Plateau, Heart Rate and Mean, Diastolic, and Systolic Pressures) with closed suction system.
Eligibility Criteria
You may qualify if:
- patients over 18 years old;
- intubated with a 7.5mm endotracheal tube;
- mechanically ventilated.
You may not qualify if:
- upper gastrointestinal bleeding;
- hemodynamic instability;
- airway bleeding;
- previous lung diseases.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Raimundo RD, Sato MA, da Silva TD, de Abreu LC, Valenti VE, Riggs DW, Perrow Carll A. Open and Closed Endotracheal Suction Systems Divergently Affect Pulmonary Function in Mechanically Ventilated Subjects. Respir Care. 2021 May;66(5):785-792. doi: 10.4187/respcare.08511. Epub 2021 Mar 9.
PMID: 33688090DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Rodrigo D Raimundo, Ph.D.
Faculdade de Medicina do ABC
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, CARE PROVIDER
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Ph.D.
Study Record Dates
First Submitted
July 18, 2017
First Posted
August 21, 2017
Study Start
February 2, 2015
Primary Completion
July 15, 2016
Study Completion
April 17, 2017
Last Updated
August 21, 2017
Record last verified: 2017-08