The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women

NCT03254251 | Completed

• 1 other identifier: PusanNU-3
• Study Type: interventional
• Target: 41
• Locations: 0 countries
• Sites: N/A

Brief Summary

We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or non-exercising control group. SC training session was progressive program, and was performed 4 days a week for 12 weeks. Measurements were collected at baseline and after 12 weeks during the same time of day (±1 hour) in the morning following an overnight fast and abstinence from caffeinated drinks, alcohol, and between 48 and 72 hours after the last exercise session.

Conditions

Hypertension; Menopause

Outcome Measures

Primary Outcomes (7)

• Arterial stiffness

  Arterial stiff ness was measured by brachial to ankle pulse wave velocity (baPWV, m/s) using volume plethysmographic device (VP-1000).

  12 weeks

• Blood pressure (BP)

  BP (mmHg) was measured by volume plethysmographic device. Diastolic blood pressure and systolic blood pressure were measured.

  12 weeks

• Muscle strength

  Muscle strength was measured by the eight repetition maximum (8RM) test using extension machine (Cyber 6000).

  12 weeks

• Body composition

  Body composition was measured using eight-polar tactile-electrode impedance meter (InBody 720). Body weight (kg), fat mass (kg), and fat free mass (kg) were assessed.

  12 weeks

• Height

  Height (m) was measured with a stadiometer

  12 weeks

• Heart rate (HR)

  Heart rate was measured by ECG

  12 weeks

• Body mass index (BMI)

  BMI was calculated as weight/height\^2 (kg/m\^2)

  12 weeks

Study Arms (2)

Stair Climbing (SC)

EXPERIMENTAL

N=20, 12 weeks of stair climbing exercise training.

Behavioral: Stair climbing

No Exercise (CON)

NO INTERVENTION

N=21, No exercise for 12 weeks

Interventions

Stair climbing BEHAVIORAL

Stair climbing (SC) training was 12 weeks of progressive SC program. Each training session consisted of a general warm-up (5 min: slow and fast skipping, stretching) followed by the SC training and was supervised by experienced personnel. The program began with two bouts of stair climbing four days a week in weeks 1 and 2, increasing by one climb a day every three weeks. By the last three weeks (10-12) of the study, all subjects were completing 5 climbs four days a week. During each climb participants ascended 12 flights (192 steps) divided into 3 sets of 4 flights, with a 2 min rest period between each set. There was a 5 min rest period between climbs that allowed the participants to reach the ground floor using an elevator. Subjects in the non-exercising control group did not participate in a supervised exercise program for the duration of the study.

Stair Climbing (SC)

Eligibility Criteria

• Age: 58 Years - 60 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Stage-1 hypertension
• Postmenopausal

You may not qualify if:

• Pulmonary, renal, adrenal, pituitary, severe psychiatric, thyroid, or cardiovascular disease other than stage-1 systolic hypertension (140-159 mmHg)
• Hormone replacement therapy during the 6 months prior the study
• Smoker or having any medication changes in the previous year
• Experience with psychological and physical therapy in the previous year
• History of steady exercise or exercise training in the last year

Sponsors & Collaborators

• Pusan National University: lead
• Dong-Eui University: collaborator
• University of Nebraska: collaborator

Related Publications (1)

• Wong A, Figueroa A, Son WM, Chernykh O, Park SY. The effects of stair climbing on arterial stiffness, blood pressure, and leg strength in postmenopausal women with stage 2 hypertension. Menopause. 2018 Jul;25(7):731-737. doi: 10.1097/GME.0000000000001072.

  PMID: 29438269 DERIVED

MeSH Terms

Conditions

Hypertension

Interventions

Stair Climbing

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Walking; Locomotion; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Exercise; Motor Activity

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: postdoctoral fellow

Study Record Dates

• First Submitted: August 16, 2017
• First Posted: August 18, 2017
• Study Start: January 9, 2017
• Primary Completion: April 3, 2017
• Study Completion: April 10, 2017
• Last Updated: November 3, 2020

Record last verified: 2020-10