Monitoring prEscriptiondruG Abuse Using DOctor Shopping bEhavior
MEGADOSE
MEGADOSE
Sponsor study identifier
observational
10,000,000
1 country
1
Study Start
December 20, 2017
Actual (reported)Primary Completion
May 20, 2018
Actual (reported)Study Completion
December 20, 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Prescription drug abuse is a major challenge in public health, in particular in countries such as France, one of the main consumers of medication in Europe. A single source of information is rarely sufficient to measure such a complex phenomenon. This project entitled MEGADOSE (Monitoring prEscriptiondruG Abuse using DOctor Shopping bEhavior) may complete efficiently the available data from the addictovigilance centres allowing the health authorities (French Drug Agency) to answer to the main general questions (What are the main prescription drug abused in France? What are the national trends in prescription drug abuse? What is the impact of a public health measure on prescription drug abuse). This project constitutes the opportunity of "extending" the application of our tool (the DS method) on a French national database with a minimal risk since this method has already been validated and applied on different geographic areas, on different drugs and at different levels of analysis. The project would also be integrated in routinely as a useful tool included in the addictovigilance monitoring, also allowing a multi-approach approach and the monitoring of policy and practice interventions implemented by the French Drug Agency. The project MEGADOSE is also in accordance with the main topic of the projects funded by ANSM related to drug misuse in particular: development and identification of systems and tools able to detect earlier misuse phenomenon; analysis of the impact of communications, guidelines, decisions to health authorities and patients
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 20, 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
August 16, 2017
Actual (reported)August 18, 2017
Actual (reported)December 20, 2017
Actual (reported)May 20, 2018
Actual (reported)December 20, 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
psychoactive drug misuse
the doctor shopping method,to assess medication availability and the extent and risk of abuse of all psychoactive reimbursed drugs at a national level according to the doctor shopping method. All psychoactive drugs will be ranked according to their DSQ (used as a proxy of the extent of abuse) and their DSI (used as a proxy of abuse potential
2 years
development and identification of systems and tools able to detect earlier misuse phenomenon
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The target population is the whole French population. The SNIIR-AM will be used as the source population. The SNIIR-AM (Systeme National d'Information Inter-Régime de l'Assurance Maladie) is the information system of the French National Health Insurance Scheme, containing individualized, anonymous, and exhaustive data on all health spending reimbursements of the overall French insured population (almost 65 million inhabitants). The information contained in this database covers the health care services reimbursed including: * Characteristics of medication dispensed (name, formulation, dates of prescription, date of dispensing, quantity dispensed and cost) * Patients characteristics including age, gender, area of residence, type of affiliation, dependency on the universal health care coverage or CMU (Couverture Médicale Universelle Complémentaire, CMUC, which is attributed to the unemployed and low income insurees, and which can be used as a proxy of the income level),
Assistance Publique Hôpitaux de Marseille
Marseille, 13354, France
Urielle Desalbres
Assistance Publique Hôpitaux de Marseille
First Submitted
August 16, 2017
First Posted
August 18, 2017
Study Start
December 20, 2017
Actual (reported)Primary Completion
May 20, 2018
Actual (reported)Contact the study team to confirm eligibility.
Study Completion
December 20, 2020
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
July 20, 2020
Record last verified: 2020-07
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