Glycemic Response of Sorghum

NCT03254082 | Completed

• 1 other identifier: KSUHML10_Sorg
• Study Type: interventional
• Target: 10
• Locations: 0 countries
• Sites: N/A

Brief Summary

Given the interest in gluten-free foods and discovering dietary means to prevent metabolic disorders, this study was designed to determine the glycemic responses of four (4) grains and flours (corn, rice, wheat, and sorghum). The grain products (gruel) will be eaten by subjects and blood glucose will be collected prior to and after eating over the course of two hours. A dextrose solution, dosed to provide a like amount of available carbohydrate, will serve as the control treatment.

Conditions

Blood Glucose

Keywords

sorghum health

Outcome Measures

Primary Outcomes (1)

• Blood glucose

  This is an acute (over 2 hours) trial to measure blood glucose (glycemic response) to food.

  Before eating (time 0) and 30, 60, 90, and 120 minutes after eating to measure the change in blood glucose due to the different food.

Study Arms (5)

F-1000 (fontanelle flour)

EXPERIMENTAL

Fontenel sorghum flour

Other: Glycemic response of F-1000

Sumac

EXPERIMENTAL

Sumac sorghum flour

Other: Glycemic response to sumac sorghum flour

Wheat

EXPERIMENTAL

Wheat flour

Other: Glycemic response to wheat flour

MMR

EXPERIMENTAL

MMR cultivar of sorghum flour -- from MMR Genetics, a company that produces sorghum seed.

Other: Glycemic response to MMR sorghum flour

Sucrose

ACTIVE COMPARATOR

Table sugar

Other: Glycemic response to sucrose

Interventions

Glycemic response of F-1000 OTHER

The intervention was to determine if different flours elicit similar or different (change from baseline) 2 hour glucose responses (e.g., similar to glycemic index) after eating.

Also known as: Fontanelle flour

F-1000 (fontanelle flour)

Glycemic response to sumac sorghum flour OTHER

The intervention was to determine the two hour change from baseline glucose responses (e.g., similar to glycemic index) after consuming sumac sorghum flour as a gruel.

Sumac

Glycemic response to MMR sorghum flour OTHER

The intervention was to determine the two hour change from baseline glucose responses (e.g., similar to glycemic index) after consuming MMR sorghum flour as a gruel.

MMR

Glycemic response to wheat flour OTHER

The intervention was to determine the two hour change from baseline glucose responses (e.g., similar to glycemic index) after consuming wheat flour as a gruel.

Wheat

Glycemic response to sucrose OTHER

The intervention was to determine the two hour change from baseline glucose responses (e.g., similar to glycemic index) after consuming sugar (dissolved in water)

Also known as: sugar

Sucrose

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Apparently healthy with no known diseases

You may not qualify if:

• Known metabolic, cancer, cardiovascular disease/condition

Sponsors & Collaborators

• Kansas State University: lead
• United Sorghum Checkoff Program: collaborator

MeSH Terms

Interventions

Sugars

Intervention Hierarchy (Ancestors)

Carbohydrates

Study Officials

• Mark Haub, PhD

  Kansas State University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: September 2, 2015
• First Posted: August 18, 2017
• Study Start: September 1, 2010
• Primary Completion: May 1, 2011
• Study Completion: May 1, 2011
• Last Updated: August 18, 2017

Record last verified: 2017-08