Relationship Between Dietary Protein Intake and Fatal and Non-fatal Health Outcomes

NCT03243578 | Completed

• 1 other identifier: UKBProHealth
• Study Type: observational
• Target: 502,628
• Locations: 0 countries
• Sites: N/A

Brief Summary

The aim of the current study was to clarify the relationship between protein intake and health by using a very large, general population cohort study, UK Biobank, to study the associations between reported protein intake (expressed in g/day, g/kg/day and % of total energy intake) and three health outcomes (all-cause mortality, incidence CVD and cancer).

Conditions

Cardiovascular Diseases; Cancer; All-cause Mortality

Outcome Measures

Primary Outcomes (3)

• All-cause mortality

  Date and cause of death were obtained from death certificates

  Mean of 7 years

• CVD incidence

  Date and cause of hospital admissions were identified via record linkage to Health Episode Statistics (HES) records for England and Wales and to the Scottish Morbidity Records (SMR01) for Scotland

  Mean of 6.1 years

• cancer incidence

  Data on cancer diagnoses for participants resident in England and Wales is provided to UK Biobank by the Medical Research Information Service, based at the National Health Service Information Centre (http://www.ic.nhs.uk/services/medical-research-informationservice). The Information Services Division (http://www.isdscotland.org/HealthTopics/Cancer/), which is a part of NHS Scotland, provides UK Biobank with the cancer data records for participants resident in Scotland.

  Mean of 6.1 years

Interventions

None as this is an observational study OTHER

Eligibility Criteria

• Age: 40 Years - 69 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Recruitment from the general population

You may qualify if:

• None

You may not qualify if:

• None

Sponsors & Collaborators

• University of Glasgow: lead

MeSH Terms

Conditions

Cardiovascular Diseases; Neoplasms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr Stuart Gray

Study Record Dates

• First Submitted: August 1, 2017
• First Posted: August 9, 2017
• Study Start: April 1, 2007
• Primary Completion: December 1, 2010
• Study Completion: January 1, 2017
• Last Updated: August 9, 2017

Record last verified: 2017-08

Data Sharing

• IPD Sharing: Will not share