Impact of Community Scabies Treatment on Head Lice Prevalence in the Solomon Islands
1 other identifier
interventional
118
1 country
1
Brief Summary
This is a pilot study evaluating if treatment for scabies also treats headlice in the same community
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_3
Started Aug 2017
Shorter than P25 for phase_3
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 26, 2017
CompletedFirst Posted
Study publicly available on registry
August 1, 2017
CompletedStudy Start
First participant enrolled
August 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
February 28, 2018
CompletedResults Posted
Study results publicly available
June 14, 2019
CompletedJune 14, 2019
November 1, 2018
5 months
July 26, 2017
November 8, 2018
March 13, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Number of Participants With Headlice
Assessed in the study population by physical examination of hair
2 Weeks after treatment
Secondary Outcomes (2)
Number of Participants With Headlice
48hrs after treatment
Number of Participants With Headlice
3 Months after treatment
Study Arms (1)
Intervention Arm
OTHERThis study consists of a single treatment arm. Patients will receive Ivermectin or where contraindicated (Pregnancy, Breastfeeding, Weight \<15kg) Permethrin Cream and Malathion shampoo
Interventions
Permethrin cream is used in conjunction with Malathion shampoo when ivermectin is contra-indicated
Permethrin cream is used in conjunction with Malathion shampoo when ivermectin is contra-indicated
Eligibility Criteria
You may qualify if:
- All participants living in the community will be offered treatment
You may not qualify if:
- Patients with a contradindication to study medication
- Patients unable to provide consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Atoifi Adventist Hospital
Atoifi, Malaita Province, Solomon Islands
Related Publications (1)
Coscione S, Esau T, Kekeubata E, Diau J, Asugeni R, MacLaren D, Steer AC, Kositz C, Marks M. Impact of ivermectin administered for scabies treatment on the prevalence of head lice in Atoifi, Solomon Islands. PLoS Negl Trop Dis. 2018 Sep 25;12(9):e0006825. doi: 10.1371/journal.pntd.0006825. eCollection 2018 Sep.
PMID: 30252856DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Dr Michael Marks
- Organization
- London School of Hygiene and Tropical Medicine
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 26, 2017
First Posted
August 1, 2017
Study Start
August 1, 2017
Primary Completion
December 31, 2017
Study Completion
February 28, 2018
Last Updated
June 14, 2019
Results First Posted
June 14, 2019
Record last verified: 2018-11