NCT03232801

Brief Summary

The overall aim of this research is to adapt and pilot test a multi-component, mindfulness-based behavioral intervention for women age 50 and older with low sexual desire.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
62

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 10, 2017

Completed
5 months until next milestone

First Posted

Study publicly available on registry

July 28, 2017

Completed
3.2 years until next milestone

Study Start

First participant enrolled

October 8, 2020

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2021

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

October 13, 2022

Completed
Last Updated

October 13, 2022

Status Verified

October 1, 2022

Enrollment Period

11 months

First QC Date

March 10, 2017

Results QC Date

August 16, 2022

Last Update Submit

October 11, 2022

Conditions

Keywords

hypoactive sexual desire disorderfemale sexual dysfunctionlow libidofemale sexual interest-arousal disorderlow desiresexual dysfunction

Outcome Measures

Primary Outcomes (2)

  • Feasibility - Number of Enrolled Women Participating in All Sessions

    Number of enrolled women participating in all sessions

    6 weeks

  • Acceptability - Number of Women Indicating "Somewhat" or "Very Satisfied" on a 5-point Likert Scale Measure of Intervention Satisfaction

    Number of women indicating "somewhat" or "very satisfied" on a 5-point Likert scale measure of intervention satisfaction

    6 weeks

Secondary Outcomes (1)

  • Change in FSFI Desire Score

    Baseline and 12 weeks

Other Outcomes (4)

  • Change in Overall Sexual Function

    Baseline and 12 weeks

  • Comprehensive Sexual Desire

    6 weeks and 12 weeks

  • Sexual Distress

    6 weeks and 12 weeks

  • +1 more other outcomes

Study Arms (2)

mindfulness group

EXPERIMENTAL

A multicomponent group-based intervention rooted in mindfulness, administered in 3 sessions over 6 weeks

Behavioral: mindfulness-based multicomponent intervention

educational group

ACTIVE COMPARATOR

A general midlife health and aging educational group, administered in 3 sessions over 6 weeks

Behavioral: general health education group

Interventions

A group-based, multicomponent behavioral intervention rooted in mindfulness

mindfulness group

A general health and aging education group

educational group

Eligibility Criteria

Age50 Years+
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailswomen participants only
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • meet criteria for a diagnosis of Female Sexual Interest/Arousal Disorder
  • English-speaking
  • have a current sexual partner with whom they are or would like to be sexually active

You may not qualify if:

  • active major depression
  • active substance abuse
  • current intimate partner violence
  • partner with active major depression
  • partner with active major substance abuse
  • significant relationship dissatisfaction
  • current use of antidepressants
  • untreated dyspareunia (sexual pain)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15213, United States

Location

MeSH Terms

Conditions

Sexual Dysfunctions, PsychologicalSexual Dysfunction, Physiological

Condition Hierarchy (Ancestors)

Mental DisordersGenital DiseasesUrogenital Diseases

Results Point of Contact

Title
Holly Thomas
Organization
University of Pittsburgh

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor of Medicine

Study Record Dates

First Submitted

March 10, 2017

First Posted

July 28, 2017

Study Start

October 8, 2020

Primary Completion

September 1, 2021

Study Completion

September 1, 2021

Last Updated

October 13, 2022

Results First Posted

October 13, 2022

Record last verified: 2022-10

Data Sharing

IPD Sharing
Will not share

Locations