Inherited CAncer REgistry

NCT03231891 | Recruiting

• 1 other identifier: VICC MD 1712
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the Inherited CAncer REgistry (ICARE) Initiative is to provide individuals interested in participating in studies focused on inherited cancer predisposition the opportunity to enroll in a research registry. Efforts through the registry include, but are not limited to, contribution of data to observational studies, targeted gene-specific studies, and education and outreach efforts for both participants and recruiting healthcare providers. Participants are given the opportunity to learn about and participate in other efforts for which they may be eligible. All participants and recruiting healthcare providers receive educational newsletters twice per year which contain research and clinical updates in the field of cancer genetics. Providers who recruit patients can also access monthly web-based genetics case conferences which focus on different topics each month and are generally attended by a guest expert who provides background information on the topic as well as comments on the case presentations. Participation in ICARE involves completion of an informed consent form, baseline questionnaire, follow-up questionnaires every two years, and medical record/tumor releases, as applicable. There is no cost to participate and all correspondence can be facilitated through phone, email, or mail. Enrollment can be completed either through a traditional paper-based consenting method (i.e. postal mail) or through the online enrollment option available on the ICARE website (InheritedCancer.net). If you are a patient interested in learning more or a provider interested in recruiting to ICARE, please visit our website where you may complete an online contact form requesting a study team member contact you.

Conditions

Cancer

Outcome Measures

Primary Outcomes (1)

• Establish and maintain a registry of individuals who are interested in participating in studies of the genetics of cancer and other related investigations.

  Up to 100 years

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals interested in participating in inherited cancer research studies.

You may qualify if:

• At least 18 years of age
• Able and willing to provide informed consent

Sponsors & Collaborators

• Vanderbilt-Ingram Cancer Center: lead

Study Sites (1)

Vanderbilt-Ingram Cancer Center

Nashville, Tennessee, 37212, United States

RECRUITING

Related Links

• Inherited Cancer Registry (ICARE) Website

Biospecimen

Retention: SAMPLES WITH DNA

Collection of blood, saliva/cheek swab, urine, and/or other biological specimens may be requested from participants. Tissues saved during previous surgeries as part of the patient's treatment may be requested.

MeSH Terms

Conditions

Neoplasms

Study Officials

• Tuya Pal, MD

  Vanderbilt University Medical Center

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Anne Weidner, MPH

CONTACT

615-875-2444; ICARE@vumc.org

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 100 Years
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Director for Cancer Health Disparities

Study Record Dates

• First Submitted: July 24, 2017
• First Posted: July 27, 2017
• Study Start: February 27, 2017
• Primary Completion (Estimated): December 1, 2034
• Study Completion (Estimated): December 1, 2035
• Last Updated: September 16, 2025

Record last verified: 2025-09

Locations

US (1)