NCT03226561

Brief Summary

Patients who underwent presbyopic correction with bilateral trifocal intraocular lenses implantation are supposed to have sufficient uncorrected vision capacity for activities of daily living (ADLs) that require near vision acuity (NV), (ie. book reading). However, it is known that light intensity and temperature has a great impact on near vision capacity. Primary objective of this study is to identify the optimal task lighting conditions (in terms of light intensity and temperature) for ADLs that demand near vision acuity for a sample of patients who underwent presbyopic correction with bilateral trifocal intraocular lenses implantation

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2017

Completed
19 days until next milestone

First Submitted

Initial submission to the registry

July 20, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

July 24, 2017

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2018

Completed
Last Updated

July 25, 2019

Status Verified

July 1, 2019

Enrollment Period

9 months

First QC Date

July 20, 2017

Last Update Submit

July 24, 2019

Conditions

Outcome Measures

Primary Outcomes (6)

  • uNVC (3000K)

    Uncorrected Near Vision Capacity at 3000 Kelvins

    6 months

  • uNVC (4000K)

    Uncorrected Near Vision Capacity at 4000 Kelvins

    6 months

  • uNVC (6000K)

    Uncorrected Near Vision Capacity at 6000 Kelvins

    6 months

  • uNVC (25FC)

    Uncorrected Near Vision Capacity at 25 Foot Candles

    6 months

  • uNVC (50FC)

    Uncorrected Near Vision Capacity at 50 Foot Candles

    6 months

  • uNVC (75FC)

    Uncorrected Near Vision Capacity at 75 Foot Candles

    6 months

Study Arms (2)

Panoptix Group

ACTIVE COMPARATOR

Patients will receive bilateral phacoemulsification with diffractive trifocal lenses implantation (Phaco / Panoptix)

Procedure: Phaco / Panoptix

Control Group

NO INTERVENTION

Control, age-matched presbyopic group corrected with presbyopic glasses

Interventions

Phacoemulsification with bilateral diffractive trifocal lens implantation

Panoptix Group

Eligibility Criteria

Age50 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Presbyopia

You may not qualify if:

  • Glaucoma Corneal pathology Fundus pathology Severe neurological/mental diseases that interfere with visual acuity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Democritus University of Thrace

Alexandroupoli, Evros, 68100, Greece

Location

Related Publications (1)

  • Labiris G, Ntonti P, Panagiotopoulou EK, Konstantinidis A, Gkika M, Dardabounis D, Perente I, Sideroudi H. Impact of light conditions on reading ability following multifocal pseudophakic corrections. Clin Ophthalmol. 2018 Dec 14;12:2639-2646. doi: 10.2147/OPTH.S180766. eCollection 2018.

MeSH Terms

Conditions

Presbyopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Study Officials

  • Georgios Labiris, MD, PhD

    Associate Professor

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

July 20, 2017

First Posted

July 24, 2017

Study Start

July 1, 2017

Primary Completion

April 1, 2018

Study Completion

June 1, 2018

Last Updated

July 25, 2019

Record last verified: 2019-07

Locations