Study on Communication Comprehension in the Schizophrenic Spectrum
SKYPROVERB
1 other identifier
interventional
59
1 country
1
Brief Summary
The purpose of the present study is to evaluate the effect of emotional prosody on the perception of emotional discourse in the schizophrenic spectrum. The investigators hypothesize that participant may use emotional prosody as an emotional cue to understand the emotional content of discourse.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Nov 2016
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 15, 2016
CompletedFirst Submitted
Initial submission to the registry
July 17, 2017
CompletedFirst Posted
Study publicly available on registry
July 21, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 27, 2019
CompletedStudy Completion
Last participant's last visit for all outcomes
May 27, 2019
CompletedJuly 29, 2019
July 1, 2019
2.5 years
July 17, 2017
July 26, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Behavioural measures (response rate and time)
Participants will have to judge the emotional intensity of audio recordings. In this task, the participant is asked to judge the emotional intensity of audio recordings of men and women (2 actors + 2 actresses): he / she must press a button as quickly as possible to indicate whether the Audio recordings presented via small speakers are very negative, negative, non-emotional, positive or very positive (5 possible choices). The response time variable may be added as a co-variable in order to avoid perceptive-motor disorders (medication-related and / or general motor slowdown) that may influence the results of time-of- answers.
During the experiment
Secondary Outcomes (2)
Symptomatic impact
During the experiment
Evaluate the cognitive functioning
During the experiment
Study Arms (3)
Patients with schizophrenia
EXPERIMENTALEmotional judgment task, post-experimental questionnaire, recognition task, detection task, questionnaire CAPE-42, trait emotional intelligence questionnaire and positive and negative syndrome scale.
Few psychotic experiences
EXPERIMENTALHealthy participants with few psychotic experience. Participants with the lowest score to the CAPE-42 test. Mini International Neuropsychiatric Interview
Several psychotic experiences
EXPERIMENTALHealthy participants with several psychotic experiences. Participants with the highest score to the CAPE-42 test. Mini International Neuropsychiatric Interview
Interventions
Participants had to indicate on a computer the emotional intensity of audio recordings.
Participants will be invited to give us the cognitive strategy used to resolve the emotional judgment task.
Participants will be invited to indicate which recordings they had heard during the emotional judgment task to verify that they have paid attention to the emotional task.
Participants indicate every time they heard a given sound in order to verify their audition level.
This questionnaire allows evaluating the nature of psychotic experiences.
To evaluate their emotional intelligence.
Evaluating the clinical status of patients with schizophrenia.
Evaluating the exclusion criteria in healthy participants.
Eligibility Criteria
You may qualify if:
- Having a diagnosis of schizophrenia and being in a stable phase of the disease
- Having between 18 to 60 years old
- Speak french or using french at school
- Accepting not to use psychoactive substances during the preceding 48h
- Being affiliated to the French social security
- Providing their written informed consent
- Having not audio deficits, nor visual uncorrected deficits
- Having not suffering from depressive symptoms during the last 6 months
You may not qualify if:
- \- Having no neurological, nor psychiatric disease except schizophrenia for the patients groups.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Hôpital NOVOlead
Study Sites (1)
HDJ François Villon
Cergy-Pontoise, 95303, France
Related Publications (3)
Brazo P, Beaucousin V, Lecardeur L, Razafimandimby A, Dollfus S. Social cognition in schizophrenic patients: the effect of semantic content and emotional prosody in the comprehension of emotional discourse. Front Psychiatry. 2014 Sep 10;5:120. doi: 10.3389/fpsyt.2014.00120. eCollection 2014.
PMID: 25309458RESULTEdwards J, Jackson HJ, Pattison PE. Emotion recognition via facial expression and affective prosody in schizophrenia: a methodological review. Clin Psychol Rev. 2002 Jul;22(6):789-832. doi: 10.1016/s0272-7358(02)00130-7.
PMID: 12214327RESULTBeaucousin V, Lacheret A, Turbelin MR, Morel M, Mazoyer B, Tzourio-Mazoyer N. FMRI study of emotional speech comprehension. Cereb Cortex. 2007 Feb;17(2):339-52. doi: 10.1093/cercor/bhj151. Epub 2006 Mar 8.
PMID: 16525130RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Mouna TRABELSI, MD
HDJ François Villon (Centre Hospitaliser René-Dubos)
- STUDY CHAIR
Virginie BEAUCOUSIN, PhD
CRFDP (University of Rouen)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 17, 2017
First Posted
July 21, 2017
Study Start
November 15, 2016
Primary Completion
May 27, 2019
Study Completion
May 27, 2019
Last Updated
July 29, 2019
Record last verified: 2019-07
Data Sharing
- IPD Sharing
- Will not share