Spherical Aberration on the Optical of Two Different Aspherical Intraocular Lenses
Effect of Spherical Aberration on the Optical Quality After Implantation of Two Different Aspherical Intraocular Lenses
1 other identifier
observational
60
0 countries
N/A
Brief Summary
Purpose: To compare the effect of spherical aberration on optical quality in eyes with two different aspherical intraocular lenses Methods: In this prospective, randomized clinical trial 120 eyes of 60 patients underwent phacoemulsification. In patient's eyes an aberration-free aspherical IOL (Aspira-aA; Human Optics) or an aberration-correcting aspherical IOL (Tecnis ZCB00; Abott Medical Optics) were randomly implanted. Three months after surgery visual acuity, contrast sensitivity, wavefront measurements with iTrace as well as tilt and decentration measurements with Visante anterior segment OCT were performed.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Sep 2015
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2016
CompletedFirst Submitted
Initial submission to the registry
July 14, 2017
CompletedFirst Posted
Study publicly available on registry
July 21, 2017
CompletedJuly 21, 2017
July 1, 2017
9 months
July 14, 2017
July 17, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Modulation transfer function (MTF) at 3 months after surgery
3 months
Study Arms (1)
2 different Intraocular lenses
2 different intraocular lenses were compared
Interventions
Eligibility Criteria
Men and women between 50 and 85 years with age related cataract
You may qualify if:
- Bilateral age-related cataract
- Potential postoperative visual acuity of 1.0 Snellen
- No relevant ocular pathology other than cataract
- Written informed consent to surgery and participation in the study
You may not qualify if:
- Amblyopia, diabetic retinopathy, uveitis or other relevant ophthalmic diseases
- Optical media disturbances due to: corneal and vitreal opacity, PEX
- Preceding ocular trauma or ocular surgery within 6 months
- Inability to cooperate
- Pregnancy (a pregnancy test will be performed preoperatively in women of reproductive age)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Lasta M, Mihaltz K, Kovacs I, Vecsei-Marlovits PV. Effect of Spherical Aberration on the Optical Quality after Implantation of Two Different Aspherical Intraocular Lenses. J Ophthalmol. 2017;2017:8039719. doi: 10.1155/2017/8039719. Epub 2017 Aug 16.
PMID: 28900544DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
July 14, 2017
First Posted
July 21, 2017
Study Start
September 1, 2015
Primary Completion
June 1, 2016
Study Completion
December 1, 2016
Last Updated
July 21, 2017
Record last verified: 2017-07