Serum AMH Levels in Patients Who Underwent Hypogastric Artery Ligation

NCT03220594 | Completed

• 1 other identifier: 1826
• Study Type: observational
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.

Conditions

AMH

Keywords

hypogastric artery; anti-mullerian hormone; ovarian reserve; postpartum

Outcome Measures

Primary Outcomes (1)

• Ovarian reserve

  To evaluate postoperative ovarian reserve using anti-mullerian hormones and other ovary related hormones including FSH,LH

  6 months

Study Arms (3)

Hypogastric artery ligation (HAL)

Patients who underwent only hypogastric artery ligation performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC)

Procedure: hypogastric artery ligation

HAL and hysterectomy

Patients who underwent both hypogastric artery ligation and hysterectomy performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC)

Procedure: hypogastric artery ligation

Postpartum

Postpartum control group constituted of patients delivered baby without any complication and evaluated 6 months later.

Interventions

hypogastric artery ligation PROCEDURE

hypogastric artery ligation is the ligation of the internal iliac artery to stop bleeding related to obstetrics obstetric hemorrhage Hysterectomy is the removal of the uterus if bleeding can't stop by hypogastric artery ligation

Also known as: hysterectomy

HAL and hysterectomy; Hypogastric artery ligation (HAL)

Eligibility Criteria

• Age: 18 Years - 40 Years
• Gender Eligibility Details: All participants are females undergoing delivery of their baby
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients who had hypogastric artery ligation and/or hysterectomy during their delivery. Control group is age-matched postpartum patients.

You may qualify if:

• age 18- 40 years
• no systemic or endocrine diseases
• patients who had hypogastric artery ligation and/or hysterectomy
• healthy postpartum patients as controls

You may not qualify if:

• history of chemotherapy and/or radiotherapy
• Obese patients
• patients with previous/present endometriosis
• patients with PCOS

Sponsors & Collaborators

• Kanuni Sultan Suleyman Training and Research Hospital: lead

Study Sites (1)

Kanuni SSTRH

Istanbul, 34303, Turkey (Türkiye)

Location

Related Links

• The effect of total abdominal hysterectomy on serum anti-Müllerian hormone levels: a pilot study
• Effect of internal iliac artery ligation on ovarian blood supply and ovarian reserve

MeSH Terms

Interventions

Hysterectomy

Intervention Hierarchy (Ancestors)

Gynecologic Surgical Procedures; Urogenital Surgical Procedures; Surgical Procedures, Operative

Study Officials

• Alev Atıs, MD,ObGyn

  Kanuni Sultan Suleyman Training and Research Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MD,ObGYN

Study Record Dates

• First Submitted: July 14, 2017
• First Posted: July 18, 2017
• Study Start: March 20, 2017
• Primary Completion: September 20, 2017
• Study Completion: September 29, 2017
• Last Updated: October 2, 2017

Record last verified: 2017-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)