NCT03220516

Brief Summary

The aim of this trial is to compare the safety, efficacy and cost effectiveness of the three types of scopes.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
450

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2017

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 1, 2017

Completed
17 days until next milestone

First Posted

Study publicly available on registry

July 18, 2017

Completed
14 days until next milestone

Study Start

First participant enrolled

August 1, 2017

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2020

Completed
Last Updated

July 18, 2017

Status Verified

July 1, 2017

Enrollment Period

3.1 years

First QC Date

July 1, 2017

Last Update Submit

July 16, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • cost of surgery

    the total cost of the procedure

    intraoperative

Secondary Outcomes (5)

  • Stone free rate

    1month after surgery

  • stone free rate

    3months after surgery

  • complication rates

    upto 3months

  • operative time

    intraoperative

  • operator's satisfaction with the scope

    intraoperative

Study Arms (3)

single-use digital ureteroscope

EXPERIMENTAL

Participants under this arm will undergo retrograde intrarenal surgery (RIRS) procedure under the single use digital ureteroscope.

Procedure: single use digital ureteroscope

reusable fiberoptic ureteroscopes

EXPERIMENTAL

Participants under this arm will undergo the RIRS procedure under the reusable fiberoptic ureteroscope

Procedure: reusable fiberoptic ureteroscope

reusable digital flexible ureteroscopes

EXPERIMENTAL

Participants under this arm will undergo the RIRS procedure under the reusable digital flexible ureteroscope.

Procedure: reusable digital flexible ureteroscope

Interventions

All participants in this arm will undergo RIRS using a single use digital ureteroscope.

single-use digital ureteroscope

All participants under this arm will undergo RIRS using a reusable fiberoptic ureteroscope

reusable fiberoptic ureteroscopes

All participants under this arm will undergo RIRS using reusable digital flexible ureteroscope

reusable digital flexible ureteroscopes

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18-70 years
  • American society of Anesthesiology (ASA) score 1 and 2
  • Renal or upper ureteral stone of diameter ≤ 2.0 cm

You may not qualify if:

  • Ureteral stricture, renal or ureteral deformity
  • Pregnancy
  • Patients with chronic kidney disease, CKD (serum creatine\> 177 umol/L)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Urolithiasis

Condition Hierarchy (Ancestors)

Urologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Doctor and Proffesor

Study Record Dates

First Submitted

July 1, 2017

First Posted

July 18, 2017

Study Start

August 1, 2017

Primary Completion

September 1, 2020

Study Completion

September 1, 2020

Last Updated

July 18, 2017

Record last verified: 2017-07