NCT03217019

Brief Summary

In neonate and infant, radial artery cannulation may be challenging and multiple attempts are required because of the small diameter. The invastigators will compare the success rates of radial arterial cannulation with a guidewire-assisted technique and the direct technique in pediatric patient(\<1yr).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 10, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 13, 2017

Completed
25 days until next milestone

Study Start

First participant enrolled

August 7, 2017

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 4, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 4, 2018

Completed
Last Updated

April 8, 2019

Status Verified

April 1, 2019

Enrollment Period

11 months

First QC Date

July 10, 2017

Last Update Submit

April 5, 2019

Conditions

Keywords

Radial ArteryVascular Catheters

Outcome Measures

Primary Outcomes (1)

  • success rate at 1st attempt (%)

    successful catheter insertion after obtaining 1st blood flush in angiocatheter.

    from arterial cannulation to successful invasive BP monitoring (up to 1 hour)

Secondary Outcomes (5)

  • total elapsed time (seconds)

    from arterial cannulation to successful invasive BP monitoring (up to 1 hour)

  • number of total cannulation attempts (number)

    from arterial cannulation to successful invasive BP monitoring (up to 1 hour)

  • number of total catheter used (number)

    from arterial cannulation to successful invasive BP monitoring (up to 1 hour)

  • malfunction of arterial line

    from the start of invasive BP monitoring until the end of anesthesia (up to 1 day)

  • complications

    from the arterial cannulation until the end of anesthesia (up to 1 day)

Study Arms (2)

Guidewire

EXPERIMENTAL

1. Radial artery puncture with direct radial pulse palpation. 2. 24G angiocatheter insertion with guidewire-assist. (Catheter over guidewire)

Procedure: Guidewire-assist

Direct

ACTIVE COMPARATOR

1. Radial artery puncture with direct radial pulse palpation. 2. 24G angiocatheter insertion without guidewire-assist. (Catheter over needle)

Procedure: Direct

Interventions

catheter insertion with guidewire-assist(catheter over guidewire)

Guidewire
DirectPROCEDURE

catheter insertion without guidewire assist(catheter over needle)

Direct

Eligibility Criteria

AgeUp to 1 Year
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Pediatric patients undergoing general anesthesia with arterial cannulation (for hemodynamic monitoring or blood sampling)

You may not qualify if:

  • Skin lesion, infection, hematoma, recent cannulation at cannulation site
  • Unstable radial pulse (d/t unstable vital sign, or arrhythmias)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jin-Tae Kim

Seoul, South Korea

Location

Related Publications (1)

  • Jang YE, Kim EH, Lee JH, Kim HS, Kim JT. Guidewire-assisted vs. direct radial arterial cannulation in neonates and infants: A randomised controlled trial. Eur J Anaesthesiol. 2019 Oct;36(10):738-744. doi: 10.1097/EJA.0000000000001064.

Study Officials

  • Jin-Tae Kim, MD, PhD

    Professor

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

July 10, 2017

First Posted

July 13, 2017

Study Start

August 7, 2017

Primary Completion

July 4, 2018

Study Completion

July 4, 2018

Last Updated

April 8, 2019

Record last verified: 2019-04

Locations