Using Mobilization Exercises on Total Knee Arthroplasty Rehabilitation

NCT03215160 | Completed

• 1 other identifier: 22595
• Study Type: interventional
• Target: 42
• Locations: 1 country
• Sites: 1

Brief Summary

There is no definite evidence about the most effective treatment approach in early-stage rehabilitation after total knee arthroplasty surgery. The purpose of this study is to investigate the effects of mobilization exercises applied with classical exercises on pain, joint range of motion, edema, function, quality of life and patient satisfaction in early stage rehabilitation after total knee arthroplasty surgery.

Conditions

Total Knee Arthroplasty; Total Knee Replacement

Keywords

Mobilization; Manual Therapies; Exercise

Outcome Measures

Primary Outcomes (1)

• Change from Baseline Range of Motion Degree at 2 weeks

  Passive knee flexion range of motion

  Baseline, Post-op 2 weeks, and Post-op 2 months

Secondary Outcomes (2)

• Change from Baseline Pain Degree at 2 weeks

  Baseline, Post-op 2 weeks, and Post-op 2 months

• Function

  Baseline, Post-op 2 weeks, and Post-op 2 months

Other Outcomes (1)

• Satisfaction levels of the patients

  At 2 months

Study Arms (2)

Mobilization Exercise Group

EXPERIMENTAL

Mobilization exercises in addition to classical exercises performed in the early post-op period

Behavioral: Exercises

Classical Exercise Group

ACTIVE COMPARATOR

only classical exercises performed in the early post-op period

Behavioral: Exercises

Interventions

Exercises BEHAVIORAL

mobilization exercises (Patellofemoral joint, Tibiofemoral joint, Soft tissue) and classical exercises performed in the early post-op period

Classical Exercise Group; Mobilization Exercise Group

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with TKA surgery due to the diagnosis of knee OA
• Between the ages of 50-75 years

You may not qualify if:

• Revision TKA,
• Previous unicompartmental arthroplasty or tibial osteotomy,
• Hemophilia,
• Rheumatic diseases,
• Lower extremity fractures and tumors,
• Neurological diseases leading to muscle weakness in the lower limbs,
• Patients with emotional and cognitive problems

Sponsors & Collaborators

• Istanbul University: lead

Study Sites (1)

Istanbul University

Istanbul, 34740, Turkey (Türkiye)

Location

Related Publications (9)

• Harvey LA, Brosseau L, Herbert RD. Continuous passive motion following total knee arthroplasty in people with arthritis. Cochrane Database Syst Rev. 2014 Feb 6;2014(2):CD004260. doi: 10.1002/14651858.CD004260.pub3.

  PMID: 24500904 BACKGROUND

• Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014 Jul;73(7):1323-30. doi: 10.1136/annrheumdis-2013-204763. Epub 2014 Feb 19.

  PMID: 24553908 BACKGROUND

• Nelson AE, Allen KD, Golightly YM, Goode AP, Jordan JM. A systematic review of recommendations and guidelines for the management of osteoarthritis: The chronic osteoarthritis management initiative of the U.S. bone and joint initiative. Semin Arthritis Rheum. 2014 Jun;43(6):701-12. doi: 10.1016/j.semarthrit.2013.11.012. Epub 2013 Dec 4.

  PMID: 24387819 BACKGROUND

• Jacobs CA, Christensen CP. Factors influencing patient satisfaction two to five years after primary total knee arthroplasty. J Arthroplasty. 2014 Jun;29(6):1189-91. doi: 10.1016/j.arth.2014.01.008. Epub 2014 Jan 21.

  PMID: 24534535 BACKGROUND

• Bade MJ, Kohrt WM, Stevens-Lapsley JE. Outcomes before and after total knee arthroplasty compared to healthy adults. J Orthop Sports Phys Ther. 2010 Sep;40(9):559-67. doi: 10.2519/jospt.2010.3317.

  PMID: 20710093 BACKGROUND

• Noble PC, Gordon MJ, Weiss JM, Reddix RN, Conditt MA, Mathis KB. Does total knee replacement restore normal knee function? Clin Orthop Relat Res. 2005 Feb;(431):157-65. doi: 10.1097/01.blo.0000150130.03519.fb.

  PMID: 15685070 BACKGROUND

• Ebert JR, Munsie C, Joss B. Guidelines for the early restoration of active knee flexion after total knee arthroplasty: implications for rehabilitation and early intervention. Arch Phys Med Rehabil. 2014 Jun;95(6):1135-40. doi: 10.1016/j.apmr.2014.02.015. Epub 2014 Mar 3.

  PMID: 24602550 BACKGROUND

• Bade MJ, Stevens-Lapsley JE. Early high-intensity rehabilitation following total knee arthroplasty improves outcomes. J Orthop Sports Phys Ther. 2011 Dec;41(12):932-41. doi: 10.2519/jospt.2011.3734. Epub 2011 Sep 30.

  PMID: 21979411 BACKGROUND

• Karaborklu Argut S, Celik D, Kilicoglu OI. The Combination of Exercise and Manual Therapy Versus Exercise Alone in Total Knee Arthroplasty Rehabilitation: A Randomized Controlled Clinical Trial. PM R. 2021 Oct;13(10):1069-1078. doi: 10.1002/pmrj.12542. Epub 2021 Feb 3.

  PMID: 33352007 DERIVED

MeSH Terms

Conditions

Motor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MSc Research Assistant

Study Record Dates

• First Submitted: June 19, 2017
• First Posted: July 12, 2017
• Study Start: July 22, 2017
• Primary Completion: December 15, 2017
• Study Completion: December 15, 2017
• Last Updated: July 18, 2018

Record last verified: 2018-07

Locations

TU (1)