NCT03212027

Brief Summary

The aim of this study is to analyze aquaporins expression of thymic epithelial tumors and to compare them with apparent diffusion coefficient(ADC) from ultra-high b-values, and to test a possibility of use of ADCuh to identify the pathological type of tumor.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jul 2017

Shorter than P25 for all trials

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 6, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

July 11, 2017

Completed
20 days until next milestone

Study Start

First participant enrolled

July 31, 2017

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2018

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2018

Completed
Last Updated

July 18, 2017

Status Verified

July 1, 2017

Enrollment Period

5 months

First QC Date

July 6, 2017

Last Update Submit

July 13, 2017

Conditions

Thymic Epithelial Tumor

Keywords

apparent diffusion coefficientaquaporins

Outcome Measures

Primary Outcomes (1)

  • Different DWI parameters in thymic epithelial tumors

    6 months

Secondary Outcomes (1)

  • To acquire aquaporins expression level of thymic epithelial tumors

    6 months

Study Arms (3)

Patients with low-risk thymomas

low-risk thymomas include types A, AB, and B1 thymomas

Patients with high-risk thymomas

high-risk thymomas include types B2 and B3 thymomas

Patients with thymic carcinomas

thymic carcinomas also called types C thymomas

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with thymic epithelial tumors

You may qualify if:

  • no use of corticosteroid drugs;
  • no MRI contraindication;
  • no infection or fever;
  • tumor diameter is greater than 2cm.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Thymic epithelial tumor

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 6, 2017

First Posted

July 11, 2017

Study Start

July 31, 2017

Primary Completion

January 1, 2018

Study Completion

May 1, 2018

Last Updated

July 18, 2017

Record last verified: 2017-07