NCT03207776

Brief Summary

Patients who are hospitalized at select Carolinas Healthcare System (CHS) sites with Chronic Obstructive Pulmonary Disorder (COPD) acute exacerbation symptoms will be treated per the CHS COPD Clinical Pathway. Patient outcomes will be followed, including but not limited to readmission. Patients on the pathway will also have access to navigator services.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,832

participants targeted

Target at P75+ for not_applicable chronic-obstructive-pulmonary-disease

Timeline
Completed

Started Jun 2017

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 12, 2017

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

June 28, 2017

Completed
7 days until next milestone

First Posted

Study publicly available on registry

July 5, 2017

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 12, 2018

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 13, 2018

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

October 14, 2019

Completed
Last Updated

April 22, 2022

Status Verified

July 1, 2020

Enrollment Period

8 months

First QC Date

June 28, 2017

Results QC Date

June 20, 2019

Last Update Submit

April 20, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Healthcare Utilization

    Occurrence of Emergency Department, inpatient, or observation encounters after the initial encounter at accrual

    60 days

Secondary Outcomes (3)

  • Quality, Comfort, and Care (QCC) Defined Readmission Rate

    30 days

  • Patient-centric (Protocol Defined) Readmission Rate

    30 days

  • 30-day COPD Specific, Acute Care Utilization to Any Hospital Within the System

    30 day

Study Arms (2)

Control

OTHER

Treatment of patients in the usual manner based on their diagnosis and resources available at that site (Usual Care).

Other: Usual Care

Intervention

OTHER

A group of 4 Usual Care components that are applied consistently and completely amongst all patients who present with COPD acute exacerbation symptoms, plus access to navigator services (COPD Clinical Pathway).

Other: COPD Clinical Pathway

Interventions

Treatment of patients in the usual manner based on their diagnosis and resources available at that site.

Control

A group of 4 Usual Care components that are applied consistently and completely amongst all patients who present with COPD acute exacerbation symptoms, plus access to navigator services.

Intervention

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Identified as having an acute exacerbation of COPD within 24 hours of admission

You may not qualify if:

  • Death during the index encounter
  • No initial discharge as of the end of the study period

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Carolinas Medical Center

Charlotte, North Carolina, 28203, United States

Location

Carolinas Healthcare System - Pineville

Charlotte, North Carolina, 28210, United States

Location

Carolinas Healthcare System - University

Charlotte, North Carolina, 28262, United States

Location

Carolinas Healthcare System - NorthEast

Concord, North Carolina, 28025, United States

Location

Carolinas Healthcare System - Kings Mountain

Kings Mountain, North Carolina, 28086, United States

Location

Carolinas Healthcare System Lincoln

Lincolnton, North Carolina, 28092, United States

Location

Carolinas Healthcare System - Union

Monroe, North Carolina, 28112, United States

Location

Carolinas Healthcare System - Cleveland

Shelby, North Carolina, 28150, United States

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Dr. Jason Roberge
Organization
Atrium Health

Study Officials

  • Daniel Howard, MD

    Wake Forest University Health Sciences

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
SEQUENTIAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 28, 2017

First Posted

July 5, 2017

Study Start

June 12, 2017

Primary Completion

February 12, 2018

Study Completion

August 13, 2018

Last Updated

April 22, 2022

Results First Posted

October 14, 2019

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations