Ultrasound Assessment of Residual Gastric Content in Critically Ill Patients

NCT03205592 | Completed

• 1 other identifier: L16-174
• Study Type: observational
• Target: 61
• Locations: 1 country
• Sites: 3

Brief Summary

This prospective observational study aims to assess whether ultrasound assessment of gastric content may be useful for the monitoring of the gastric residual content in critically ill patients

Conditions

Critically Ill Patients

Outcome Measures

Primary Outcomes (2)

• change in antral cross sectional area measured by ultrasonography after suctioning gastric volume

  Ultrasound measurement of antral area and qualitative assessment

  prior to and immediately after suctioning of gastric content volume through a gastric tube

• Change in antral area after administration of prokinetic drug

  If aspirated gastric content volume was \> 250 ml, only 250 ml will be reinjected into the stomach and a prokientic drug will be administered (current protocol in our units). Antral area will be measured prior to and 90 min after the start of the infusion

  Ultrasound assessment of gastric content after reinjection of suctioned gastric content and 1h30 later (1 h after the end of the infusion of prokinetic drug)

Interventions

Ultrasound examination of the antrum DIAGNOSTIC_TEST

Ultrasound assessment of gastric content will be performed : prior to suction of gastric content through a gastric tube (method to assess the residual gastric content volume), after this suctioning of gastric content, then after reinjection of the content suctioned into the stomach (max 250 ml) and 1h30 later

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Critically ill patients hospitalized in 3 critical care units (Groupement hospitalier Sud Lyon, Saint Etienne, Marseille)

You may qualify if:

• Critically ill patients under mechanical ventilation and enteral feeding through a gastric tube since \>48 h

You may not qualify if:

• Digestive hemorrhage Contra-indication to prokinetic drugs Enteral feeding through jejunostomy or gastrostomy Pregnancy

Sponsors & Collaborators

• Hôpital Edouard Herriot: lead

Study Sites (3)

Hôpital Nord

Marseille, 13015, France

Location

Centre Hospitalier Lyon Sud

Pierre-Bénite, 69310, France

Location

CHU Saint Etienne

Saint-Etienne, 42000, France

Location

Related Publications (1)

• Bouvet L, Zieleskiewicz L, Loubradou E, Alain A, Morel J, Argaud L, Chassard D, Leone M, Allaouchiche B; AzuRea CAR'Echo collaborative networks. Reliability of gastric suctioning compared with ultrasound assessment of residual gastric volume: a prospective multicentre cohort study. Anaesthesia. 2020 Mar;75(3):323-330. doi: 10.1111/anae.14915. Epub 2019 Dec 4.

  PMID: 31802485 DERIVED

Study Officials

• Lionel BOUVET, MD PhD

  Hospices Civils de Lyon

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: June 28, 2017
• First Posted: July 2, 2017
• Study Start: July 3, 2017
• Primary Completion: May 4, 2018
• Study Completion: May 4, 2018
• Last Updated: May 7, 2018

Record last verified: 2018-05

Locations

FR (3)