Evaluating the Fluid Balance of Mechanically Ventilated Patients by Ultrasonography

NCT03204292 | Completed

• 1 other identifier: 122.6120.85.2015
• Study Type: observational
• Target: 57
• Locations: 1 country
• Sites: 1

Brief Summary

ratio of the diameter of inferior vena cava to the diameter of the thoracic aorta (IVC / Ao) depends on the daily balance of fluids.

Conditions

Fluid Overload; Fluid Loss

Keywords

Inferior vena cava; Fluid responsiveness; Central venous pressure

Outcome Measures

Primary Outcomes (1)

• fluid balance

  the width of the vena cava and abdominal aorta was measured every day morning. The difference in in taken and excreted fluids

  1 day

Study Arms (1)

IVC/Ao

ultrasound, the inferior vena cava and abdominal aorta were measured. Inferior vena cava width was assessed at an interval of approximately 1 cm distal from connection of the hepatic vein to the inferior vena cava. No significant changes were observed in the width of the inferior vena cava during various respiratory phases, because of the positive pressure ventilation. The widest value was always chosen for the data. The assessment of the width of the abdominal aorta was performed above arise of the celiac trunk, at the height of the vein of the lower vena cava.

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

There were 57 mechanically ventilated patients examined. 8 patients were excluded from the study because of spontaneous ventilation within 5 days of data collection. Two patients died during the study. Five patients failed to obtain satisfactory results of imaging of vascular structures during subsequent examination. Data from 42 patients were analyzed.

You may qualify if:

• patients who were hospitalized in the Intensive Care Unit
• severe respiratory failure requiring mechanical ventilation

You may not qualify if:

• spontaneous breathing,
• severe vascular disease,
• increased intra-abdominal pressure,
• cardiac pacemaker
• cardioverter defibrillator

Sponsors & Collaborators

• Jagiellonian University: lead

Study Sites (1)

University Hospital

Krakow, Lesser Poland Voivodeship, 31-501, Poland

Location

MeSH Terms

Conditions

Edema

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Tomasz Skladzien, Ph.D.

  Jagiellonian University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: senior assistant

Study Record Dates

• First Submitted: June 24, 2017
• First Posted: July 2, 2017
• Study Start: July 1, 2015
• Primary Completion: January 1, 2017
• Study Completion: January 1, 2017
• Last Updated: July 2, 2017

Record last verified: 2017-06

Data Sharing

• IPD Sharing: Will not share

Locations

PL (1)