NCT03200366

Brief Summary

The purpose of this study is to test different approaches to help people understand the purpose of colorectal cancer (CRC) screening, two screening test options available, and the barriers to screening so they can make informed decisions about CRC screening. Participants will be randomly assigned to one of three groups: (1) one group will receive a tailored digital video disc (DVD) in the mail; (2) another group will receive the mailed DVD plus telephone calls from a patient navigator; and (3) the third group will receive the care normally provided by the healthcare system's endoscopy department. The investigators hypothesize the following: (1) participants who receive the tailored DVD plus the patient navigation intervention will have higher rates of CRC screening with the fecal immunochemical test (FIT), colonoscopy, or either screening test compared to those who receive the tailored DVD alone; (2) participants who receive either intervention (DVD only or DVD plus patient navigation) will have higher rates of CRC screening with FIT, colonoscopy, or either screening test than those who receive usual care; and (3) participants who receive either intervention who complete colonoscopy will have better quality of bowel preparation, less anxiety about the procedure, and greater satisfaction with the colonoscopy experience than those who receive usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
371

participants targeted

Target at P50-P75 for not_applicable colorectal-cancer

Timeline
Completed

Started Jul 2017

Typical duration for not_applicable colorectal-cancer

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 22, 2017

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 27, 2017

Completed
29 days until next milestone

Study Start

First participant enrolled

July 26, 2017

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 21, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 21, 2020

Completed
11 months until next milestone

Results Posted

Study results publicly available

September 13, 2021

Completed
Last Updated

September 13, 2021

Status Verified

August 1, 2021

Enrollment Period

3.2 years

First QC Date

June 22, 2017

Results QC Date

June 8, 2021

Last Update Submit

August 16, 2021

Conditions

Keywords

Cancer Screening TestsColonoscopy

Outcome Measures

Primary Outcomes (1)

  • Participants Completing CRC Screening Per Electronic Medical Record Documentation

    Number of participants completing CRC screening by any test (defined as colonoscopy or FIT) is measured by electronic medical record review. Dates that participants had a colonoscopy and dates of FIT analysis are extracted from the electronic medical record.

    12 months post-baseline interview

Secondary Outcomes (18)

  • Participants Completing Colonoscopy Per Electronic Medical Record Documentation

    12 months post-baseline interview

  • Bowel Preparation Quality Rating Using Boston Bowel Preparation Scale

    12 months post-baseline interview

  • Participants With Adequate Quality of Bowel Preparation Per Modified Aronchick Rating Scale

    12 months post-baseline interview

  • Colonoscopy-Related Procedural Anxiety for Participants Completing a Colonoscopy

    12 months post-baseline interview

  • Satisfaction With Colonoscopy Experience

    12 months post-baseline interview

  • +13 more secondary outcomes

Study Arms (3)

Tailored DVD

ACTIVE COMPARATOR

Tailored digital video disc (DVD)

Behavioral: Tailored DVD

Tailored DVD + Patient Navigation

ACTIVE COMPARATOR

Tailored digital video disc (DVD) plus Patient Navigation by a population health nurse in the healthcare system

Behavioral: Tailored DVDBehavioral: Patient Navigation

Usual Care

NO INTERVENTION

Care normally provided by a nurse in the endoscopy department of the healthcare system

Interventions

Tailored DVDBEHAVIORAL

A 20 minute tailored DVD titled "Approaches to Colon Testing" is viewed by participants. It is designed to encourage CRC screening uptake by colonoscopy or FIT by increasing the participant's CRC knowledge and beliefs about the benefits of screening, reducing barriers to screening, and increasing self-efficacy for screening by demonstrating how these tests are performed.

Tailored DVDTailored DVD + Patient Navigation

Participants talk by telephone with a Patient Navigator who is a trained nurse. The Patient Navigator determines if participants viewed the tailored DVD and answers any questions about the content. The Patient Navigator then provides telephone counseling on CRC and screening tests to: (1) increase knowledge, perceived benefits, and self-efficacy; (2) reduce barriers; (3) enhance access; and (4) provide social support.

Tailored DVD + Patient Navigation

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Referred for a screening colonoscopy that was not done (i.e, canceled or no show)

You may not qualify if:

  • Unable to speak, read, and write English
  • Personal history of CRC or polyps
  • Personal history of conditions that place participants at high risk for CRC such as ulcerative colitis, Crohn's disease, or known hereditary syndromes such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer
  • Family history of CRC which increases the participant's risk for CRC
  • Advised by a health care provider to not have a colonoscopy due to the participant's health
  • Speech impairment
  • Hearing impairment
  • Cognitive impairment
  • Vision impairment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Eskenazi Health

Indianapolis, Indiana, 46202, United States

Location

Indiana University School of Nursing

Indianapolis, Indiana, 46202, United States

Location

MeSH Terms

Conditions

Colorectal Neoplasms

Interventions

Patient Navigation

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Intervention Hierarchy (Ancestors)

Patient-Centered CarePrimary Health CareComprehensive Health CarePatient Care ManagementHealth Services Administration

Results Point of Contact

Title
Susan M. Rawl, PhD, RN, FAAHB, FAAN
Organization
Indiana University

Study Officials

  • Susan M Rawl, PhD,RN

    Indiana University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

June 22, 2017

First Posted

June 27, 2017

Study Start

July 26, 2017

Primary Completion

October 21, 2020

Study Completion

October 21, 2020

Last Updated

September 13, 2021

Results First Posted

September 13, 2021

Record last verified: 2021-08

Data Sharing

IPD Sharing
Will share

A copy of the complete, cleaned, de-identified data set used to conduct the final analyses will be made available in SAS and SPSS formats.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Available by September 30, 2021
Access Criteria
Request in writing to the the study's Principal Investigator, Dr. Susan Rawl

Locations