Frequency of Asymptomatic Left Ventricular Diastolic Dysfunction in Diabetes Mellitus Type 2

NCT03196687 | Unknown DMC

• 1 other identifier: assiut university9000
• Study Type: observational
• Target: 100
• Locations: 0 countries
• Sites: N/A

Brief Summary

Patients with type 2 DM may develop a cardiomyopathy often called diabetic cardiomyopathy which is characterized by left ventricular diastolic dysfunction in early stages Type 2 DM is associated with various types of subclinical target organ damage resulting in elevated risk of CVD events, moreover there is growing evidence that a prediabetic status, such as impaired fasting glucose is also related to subclinical target organ damage when compared to a group with normal glucose metabolism Diabetes mellitus is a well-studied major risk factor for coronary heart diseases, which is one of the leading causes of death worldwide. Another distinct entity of diabetes-related cardiac affection is the diabetic cardiomyopathy. This entity of cardic affection by diabetes still needs more and more attention, not only because it is common in diabetic patients, but also because of its easy detection by the simple, inexpensive and widely available diagnostic echocardiography.

Conditions

Diastolic Dysfunction

Keywords

diastolic dysfunction

Outcome Measures

Primary Outcomes (1)

• percentage of Frequency of asymptomatic left ventricular diastolic dysfunction in diabetes mellitus type 2

  1 year

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Will assess the prevelance and frequency of diastolic dysfunction of the left ventricle in patients with asymptomatic type 2 DM and to explore its relation to other parameters, including patients' age, sex, the duration of diabetes and glycemic control.

You may qualify if:

• DM type 2 who are asymptomatic of any cardiac symptom.

You may not qualify if:

• Patients of known hypertension with or without treatment.
• Cardiac arrhythmias.
• Cardiomyopathy.
• Valvular heart disease.
• Heart failure.
• Chronic pulmonary disease.
• Extreme age.
• Chronic renal failure.
• Subjects with poor transthoracic echo window.

Sponsors & Collaborators

• Assiut University: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assiut University

Study Record Dates

• First Submitted: May 6, 2017
• First Posted: June 23, 2017
• Study Start: July 1, 2017
• Primary Completion: June 1, 2018
• Study Completion: June 1, 2018
• Last Updated: June 23, 2017

Record last verified: 2017-05