Pulmonary Physiotherapy for Ischemic Stroke

NCT03195907 | Completed

• 1 other identifier: StrokePPT
• Study Type: observational
• Target: 181
• Locations: 1 country
• Sites: 1

Brief Summary

This study evaluates the predictors of intensive care unit admission and mortality among stroke patients and the effects of pulmonary physiotherapy on these stroke patients. One-hundred patients participated in the pulmonary rehabilitation program and 81 patients served as a control group.

Conditions

Stroke, Ischemic; Intensive Care Neurological Disorder; Morality; Rehabilitation

Keywords

Stroke; Mortality; Intensive care unit; Pulmonary rehabilitation

Outcome Measures

Primary Outcomes (1)

• Intensive care unit admission

  Patients who require mechanical ventilation were admitted to the neurological intensive care unit

  3 months

Secondary Outcomes (4)

• Mortality rates

  3 months

• Assessment of stroke severity

  3 months

• Assessment of functional disability

  3 months

• Pneumonia onset

  3 months

Study Arms (2)

PPT group

Those participated in pulmonary rehabilitation program

Other: Pulmonary physiotherapy

Control group

Those served as control group

Interventions

Pulmonary physiotherapy OTHER

PPT group

Eligibility Criteria

• Age: 40 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who were admitted to the neurology clinic stroke unit or the neurological intensive care unit

You may qualify if:

• acute ischemic stroke confirmed by computed tomography or a diffusion-weighed magnetic resonance imaging scan,
• aged \> 40 years,
• ability to understand and follow simple verbal instructions,
• modified Rankin scale score \> 2,
• National Institute of Health Stroke Scale score \> 0,
• no unrestricted movement of the lips,
• no receptive aphasia and no history of thoracic or abdominal surgery.

You may not qualify if:

• blood pressure \>180/100 mm Hg more than twice in 24 h;
• significant pulmonary disease, angina, myocardial infarction or acute heart failure within three months;
• neurological conditions other than stroke;
• presence of a severe visual disability and visual field defects;
• receiving medications that would influence the metabolic or cardiorespiratory responses to exercise;
• inability to perform the tests.

Sponsors & Collaborators

• Abdulkadir Tunc: lead

Study Sites (1)

Sakarya University

Sakarya, Serdivan, 54050, Turkey (Türkiye)

Location

Related Publications (6)

• Seo K, Hwan PS, Park K. The effects of inspiratory diaphragm breathing exercise and expiratory pursed-lip breathing exercise on chronic stroke patients' respiratory muscle activation. J Phys Ther Sci. 2017 Mar;29(3):465-469. doi: 10.1589/jpts.29.465. Epub 2017 Mar 22.

  PMID: 28356632 RESULT

• Lan MY, Wu SJ, Chang YY, Chen WH, Lai SL, Liu JS. Neurologic and non-neurologic predictors of mortality in ischemic stroke patients admitted to the intensive care unit. J Formos Med Assoc. 2006 Aug;105(8):653-8. doi: 10.1016/S0929-6646(09)60164-9.

  PMID: 16935766 RESULT

• Grube MM, Koennecke HC, Walter G, Meisel A, Sobesky J, Nolte CH, Wellwood I, Heuschmann PU; Berlin Stroke Register (BSR). Influence of acute complications on outcome 3 months after ischemic stroke. PLoS One. 2013 Sep 24;8(9):e75719. doi: 10.1371/journal.pone.0075719. eCollection 2013.

  PMID: 24086621 RESULT

• Kim J, Park JH, Yim J. Effects of respiratory muscle and endurance training using an individualized training device on the pulmonary function and exercise capacity in stroke patients. Med Sci Monit. 2014 Dec 5;20:2543-9. doi: 10.12659/MSM.891112.

  PMID: 25488849 RESULT

• Katz-Leurer M, Shochina M, Carmeli E, Friedlander Y. The influence of early aerobic training on the functional capacity in patients with cerebrovascular accident at the subacute stage. Arch Phys Med Rehabil. 2003 Nov;84(11):1609-14. doi: 10.1053/s0003-9993(03)00344-7.

  PMID: 14639559 RESULT

• Gungen BD, Tunc A, Aras YG, Gundogdu AA, Gungen AC, Bal S. Predictors of intensive care unit admission and mortality in patients with ischemic stroke: investigating the effects of a pulmonary rehabilitation program. BMC Neurol. 2017 Jul 11;17(1):132. doi: 10.1186/s12883-017-0912-4.

  PMID: 28693521 DERIVED

MeSH Terms

Conditions

Ischemic Stroke; Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Abdulkadir TUNÇ, MD

  Bezmialem Vakif University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Neurologist

Study Record Dates

• First Submitted: June 20, 2017
• First Posted: June 22, 2017
• Study Start: February 1, 2015
• Primary Completion: January 1, 2016
• Study Completion: January 1, 2016
• Last Updated: June 22, 2017

Record last verified: 2017-06

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)