NCT03195439

Brief Summary

The study has 2 phases:

  • The Retrospective Phase (50 patients were diagnosed to have sepsis according to our definition and criteria and 30 patients as a controlled cases )
  • The Prospective Phase (600 patients who will be admitted and monitored in ICU in order to get at least 30 sepsis cases, according to our definition and criteria). Measurements will be made from the forehead using the TTP's biocompatible sensor Unit that will be attached to the skin. The SU will transfer data to the MCU.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
600

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2017

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 12, 2017

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 22, 2017

Completed
3 months until next milestone

Study Start

First participant enrolled

October 1, 2017

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2019

Completed
Last Updated

June 22, 2017

Status Verified

June 1, 2017

Enrollment Period

1.5 years

First QC Date

June 12, 2017

Last Update Submit

June 19, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Continuously measure body temperature using TTP

    During the trial, temperature measurements will be conducted using the TTP™ and currently used thermometers which are in routine use, later to be regarded as reference methods To examine the effectiveness of the TTP™ as a measure for detection of temperature changes pattern and to correlate such changes with fever related to infections such as sepsis.

    Estimated time frame of the trial is 18 months.

Study Arms (1)

patients in ICU

EXPERIMENTAL
Device: TTP

Interventions

TTPDEVICE

TTP™ allows to continuously measure body temperature using a new non-invasive method, and was cleared for marketing by US FDA (K150160) for as a temperature monitoring system intended to measure and monitor core body temperature of patients of all ages, by applying a sensor unit on the forehead.

patients in ICU

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • The Retrospective Phase
  • Both genders (Male or Female).
  • Aged 18 years and/or above.
  • Patients were Admitted to our ICU for more than 3 days, and shall be at least 72 hours prior to sepsis or infection detection in the ICU The Prospective Phase
  • Both genders (Male or Female).
  • Aged 18 years and/or above. Patients expected to be admitted to our ICU for more than 3 days

You may not qualify if:

  • The patients will be excluded from the trial if one of the following occurs:
  • The Retrospective Phase
  • \- The medical staff decides that the patien t should not participate.
  • Unavailable measurement site in case of head injury in the head area.
  • Unavailable measurement reading during admission to ICU

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hadassah Medical Center

Jerusalem, POB 12000, Israel

Location

Central Study Contacts

Vered Nehemia, MD

CONTACT

Olga Yakov, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 12, 2017

First Posted

June 22, 2017

Study Start

October 1, 2017

Primary Completion

April 1, 2019

Study Completion

October 1, 2019

Last Updated

June 22, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will not share

Locations