NCT03190876

Brief Summary

With a prevalence of up to 25%, seroma formation is among the most common complications of body contouring procedures such as abdominoplasty. Small amounts of fluid are reabsorbed by the body spontaneously, however, larger seroma volumes need to be evacuated via puncture aspiration to prevent wound healing disturbances and infection, leading to major patient discomfort and a prolonged hospital stay. There is increasing controversy regarding the efficacy of surgical drains in seroma prevention. This study compares the incidence rate of seroma in three study arms with different usage of drains.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2017

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 15, 2017

Completed
4 days until next milestone

First Posted

Study publicly available on registry

June 19, 2017

Completed
4.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2022

Completed
Last Updated

May 3, 2019

Status Verified

May 1, 2019

Enrollment Period

5 years

First QC Date

June 15, 2017

Last Update Submit

May 1, 2019

Conditions

Keywords

Drain usage

Outcome Measures

Primary Outcomes (1)

  • Rate of seroma formation

    As primary outcome this study measures the rate of seroma requiring evacuation via puncture aspiration (fluid retention \> 20 cc) in each group.

    Weekly follow-up until postoperative week 6.

Study Arms (3)

Suction drain

NO INTERVENTION

Conventional body contouring procedure, application of Redon suction drains, drain removal when output is less than 30 ml in 24 hours or at the latest on postoperative day 7

Passive drain

ACTIVE COMPARATOR

Conventional body contouring procedure, application of drains without suction (passive drainage), drain removal when output is less than 30 ml in 24 hours or at the latest on postoperative day 7

Procedure: Variable drain usage

No drain

ACTIVE COMPARATOR

Conventional body contouring procedure, no application of drains

Procedure: Variable drain usage

Interventions

Influence of drain usage on seroma formation rate

No drainPassive drain

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All full-aged patients requiring body contouring procedures in our department who provide oral and written informed consent indicating that they agree to participate in the study

You may not qualify if:

  • Minors or patients with a designated health care proxy, revision surgeries, morbid obesity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Plastic Surgery, University Hospital of Regensburg

Regensburg, Bavaria, 93053, Germany

RECRUITING

MeSH Terms

Conditions

Seroma

Condition Hierarchy (Ancestors)

InflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Alexandra Anker, Dr. med. univ.

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 15, 2017

First Posted

June 19, 2017

Study Start

March 1, 2017

Primary Completion

March 1, 2022

Study Completion

March 1, 2022

Last Updated

May 3, 2019

Record last verified: 2019-05

Data Sharing

IPD Sharing
Will not share

Locations