NCT03190850

Brief Summary

This study aims to evaluate the effect of inspiratory muscle training on sleep apnea in the elderly. The patients screened will be randomized and allocated into two groups, intervention and control. In the intervention group, the patients will perform the exercises with the inspiratory muscular training apparatus called Powerbreathe with progressive load, according to its inspiratory muscular force. The control group will perform the same exercises, with the same apparatus, but without load.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Apr 2016

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 5, 2016

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

March 23, 2017

Completed
3 months until next milestone

First Posted

Study publicly available on registry

June 19, 2017

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 9, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 10, 2018

Completed
Last Updated

June 19, 2017

Status Verified

June 1, 2017

Enrollment Period

1.9 years

First QC Date

March 23, 2017

Last Update Submit

June 15, 2017

Conditions

Keywords

Sleep ApneaElderlyInspiratory training

Outcome Measures

Primary Outcomes (1)

  • Effect of inspiratory exercise on apnea-hypopnea index in elderly patients with sleep apnea.

    Impact of inspiratory muscle training on apnea-hypopnea index in elderly patients with sleep apnea. The measurement will be taken before and after the training. The measurement is apnea-hypopnea index through polysomnograph

    8 weeks

Secondary Outcomes (2)

  • Effect of inspiratory training on maximal inspiratory and expiratory pressures

    8 weeks

  • Effect of inspiratory muscle training on diaphragm thickness

    8 weeks

Study Arms (2)

Intervention

EXPERIMENTAL

Intervention: Exercises wih load Device: "Powerbreathe"

Other: Intervention

Control

PLACEBO COMPARATOR

Control: Exercises without load

Other: Control

Interventions

The device in which the breathing exercises will be performed will be adjusted with progressive loading aiming to improve muscular strength

Intervention
ControlOTHER

The device in which the breathing exercises will be performed will not be adjusted with progressive loading.

Control

Eligibility Criteria

Age65 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Age between 65 and 80 years
  • Both genders
  • Not be treating apnea with AHI between 10 and 30
  • Do not tolerate or not have access to CPAP with any AHI
  • To consent to participate in the research

You may not qualify if:

  • Treatment for sleep apnea
  • Severe chronic illness
  • IAH greater than 35
  • Uncontrolled arterial hypertension
  • Acute myocardial infarction
  • Recent upper airway trauma
  • High performance athletes
  • Medications with effect on the central nervous system

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital de Clinicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90035903, Brazil

RECRUITING

MeSH Terms

Conditions

Sleep Apnea, ObstructiveSleep Apnea Syndromes

Interventions

Methods

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Intervention Hierarchy (Ancestors)

Investigative Techniques

Study Officials

  • Denis Martinez

    PhD of Graduate Program in Medical Sciences

    STUDY DIRECTOR

Central Study Contacts

Denis Martinez

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Masking Details
The investigator will not know the final result of the tests performed until the end of the study
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 23, 2017

First Posted

June 19, 2017

Study Start

April 5, 2016

Primary Completion

March 9, 2018

Study Completion

May 10, 2018

Last Updated

June 19, 2017

Record last verified: 2017-06

Locations