NCT03190200

Brief Summary

The purpose of the study is to determine if by using MRI changes can be identified changes early on in the knees of young children that may be at risk for developing osteochondritis dissecans. If MRI can identify changes then better council can be offered about the risks of future activity and treatment options.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
7

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 14, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 16, 2017

Completed
7 months until next milestone

Study Start

First participant enrolled

January 1, 2018

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2022

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

August 3, 2023

Status Verified

August 1, 2023

Enrollment Period

4.9 years

First QC Date

June 14, 2017

Last Update Submit

August 2, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • OCD

    The Development of Osteochondritis Dissecans is the outcome of interest

    18 months

Study Arms (1)

MRI

Subjects with healthy knees

Device: MRI

Interventions

MRIDEVICE

No intervention - observational trial using MRI

MRI

Eligibility Criteria

Age6 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

6-10-year-old children with a sibling with known OCD and 6-10-year-old children with a known OCD in the contralateral knee

You may qualify if:

  • year-old children with a sibling with known OCD and 6-10-year-old children with a known OCD in the contralateral knee

You may not qualify if:

  • Unable to undergo an MRI

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Minnesota

Minneapolis, Minnesota, 55454, United States

Location

MeSH Terms

Conditions

Osteochondritis Dissecans

Condition Hierarchy (Ancestors)

OsteochondritisBone DiseasesMusculoskeletal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 14, 2017

First Posted

June 16, 2017

Study Start

January 1, 2018

Primary Completion

December 1, 2022

Study Completion

July 1, 2023

Last Updated

August 3, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will not share

Locations