NCT03187886|Terminated
Use Lay Language. CAA-ri : a Series of 28 Patients
A Clinico-radiological Reappraisal of Cerebral Amyloid Angiopathy-related Inflammation in a Series of 28 Patients.
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A Clinico-radiological Reappraisal of Cerebral Amyloid Angiopathy-related Inflammation in a Series of 28 Patients.
Sponsor study identifier
observational
28
0 countries
N/A
Study Start
January 1, 2017
Actual (reported)Primary Completion
June 12, 2017
Actual (reported)Study Completion
July 31, 2017
Actual (reported)INTRODUCTION: Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a very rare manifestation of cerebral amyloid angiopathy, characterized by acute/subacute neurological deterioration and T2/FLAIR corticosubcortical or deep white matter hyperintensity. With the advent of new diagnostic criteria, there are more and more case reports and series reported; nevertheless, MRI findings and follow-up data need to be thoroughly described. OBJECTIVES: Our aim in this multicentrical and retrospective study was to describe the clinical and radiological features of patients with CAA-ri and assess long-term prognosis. METHODS: We reviewed the characteristics of 28 patients with CAA-ri including clinical data, systematic MRI analysis, cerebrospinal fluid results (including Alzheimer's disease biomarkers) and APOE genotype. HYPOTHESIS: We aimed at describing the clinical and radiological characteristics of a cohort of patients with CAA-ri.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
July 31, 2017
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2017
Actual (reported)June 12, 2017
Actual (reported)June 12, 2017
Actual (reported)June 15, 2017
Actual (reported)July 31, 2017
Actual (reported)MRI results
MRI results and Follow-up
1 day
cerebral amyloid angiopathy related inflammation
Xavier AYRIGNAC, MD
University Hospital, Montpellier
28 participants (actual enrollment reported by the registry).
First Submitted
June 12, 2017
First Posted
June 15, 2017
Study Start
January 1, 2017
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
June 12, 2017
Actual (reported)Study Completion
July 31, 2017
Actual (reported)Last Updated
December 5, 2017
Record last verified: 2017-06
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