NCT03183349

Brief Summary

20 subjects suffering from non restorable maxillary premolar teeth will be randomly devided into two groups. the selected teeth will be extracted and immeiate implants will be placed in all subjects. the first group will recieve deprotienized bovine bone (tutogen) to fill the buccal space between the implant and the bone, the second group will recieve platlet rich fibrin to fill the buccal space between the implant and the bone

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2016

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2016

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2017

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

June 6, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 12, 2017

Completed
19 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2017

Completed
Last Updated

June 14, 2017

Status Verified

June 1, 2017

Enrollment Period

11 months

First QC Date

June 6, 2017

Last Update Submit

June 10, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Patient morbidity

    patient pain level on pain scale using pain chart

    14 days

Secondary Outcomes (2)

  • crestal bone loss

    3 months

  • implants stability quotient

    3 months

Study Arms (2)

platelet rich fibrin

EXPERIMENTAL

immediate implant grafting

Procedure: deprotienized bovine bone (tutogen)

deprotienized bovine bone (tutogen)

ACTIVE COMPARATOR

immediate implant grafting

Procedure: platelet rich fibrin

Interventions

platelet rich fibrin
deprotienized bovine bone (tutogen)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • non restorable maxillary premolars non smoker free from any systemic disease or medication that could impair normal bone healing

You may not qualify if:

  • any systemic disease that could affect bone healing patient with lesion related to the surgical site

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 6, 2017

First Posted

June 12, 2017

Study Start

July 1, 2016

Primary Completion

June 1, 2017

Study Completion

July 1, 2017

Last Updated

June 14, 2017

Record last verified: 2017-06

Data Sharing

IPD Sharing
Will share