Computerized Training for Individuals Diagnosed With Obsessive-Compulsive and Related Disorders

NCT03182075 | Completed

• 1 other identifier: 40185
• Study Type: interventional
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

Obsessive-Compulsive Disorder (OCD) is a chronic and disabling disorder that costs the economy over $2 billion annually and represents a significant public health problem. This study aims to build on our understanding of aberrant emotional processing in OCD. The proposed project tests whether a computerized training aimed to alter emotional processes, can relieve repetitive thoughts and behaviors.

Conditions

Obsessive Compulsive Disorder

Keywords

Obsessive-Compulsive Disorder; OCD; Obsessive Personality Disorder; Compulsive Behavior; Personality Disorders; Mental Disorders; Anxiety Disorders; Impulsive Behavior; Cognition; Emotion; Emotional Regulation

Outcome Measures

Primary Outcomes (2)

• Yale-Brown Obsessive Compulsive Scale (for participants diagnosed with OCD)

  Improvement in OCD severity is measured by the YBOCS (Yale Brown Obsessive-Compulsive Scale), a gold standard measure of obsessions and compulsions. For the YBOCS the minimum units are 0 and Maximum units on the total scale are 40. The higher the number on the YBOCS, the more severe the symptoms. Response is defined as at least a 35% reduction on the YBOCS.

  up to 2 months

• Savings Inventory Revised Scale (for participants diagnosed with hoarding disorder)

  The SI-R is a 23-item questionnaire with 3 factor-analytically defined sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition.

  up to 2 months

Study Arms (2)

Active Training

EXPERIMENTAL

OCD and hoarding disorder participants will receive active emotional reactivity training (14 sessions) via computer.

Behavioral: Computerized Training

Passive Training

SHAM COMPARATOR

OCD and hoarding disorder participants will receive passive computerized training (14 sessions) via computer.

Behavioral: Computerized Training

Interventions

Computerized Training BEHAVIORAL

OCD and hoarding disorder participants will receive 14 sessions of training via computer within 3 weeks.

Active Training; Passive Training

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age 18 years old and older
• primary diagnosis of OCD
• sufficient severity of OCD symptoms
• Stable on psychotropic or other medication
• capacity to provide informed consent

You may not qualify if:

• psychiatric or medical conditions that make participation unsafe
• concurrent use of any medications that might increase the risk of participation
• concurrent Cognitive-Behavioral therapy for OCD

Sponsors & Collaborators

• Stanford University: lead

Study Sites (1)

Stanford University

Stanford, California, 94305, United States

Location

Related Links

• Rodriguez Lab Website

MeSH Terms

Conditions

Obsessive-Compulsive Disorder; Compulsive Personality Disorder; Compulsive Behavior; Personality Disorders; Mental Disorders; Anxiety Disorders; Impulsive Behavior; Emotional Regulation

Condition Hierarchy (Ancestors)

Behavior; Self-Control; Social Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: June 7, 2017
• First Posted: June 9, 2017
• Study Start: April 30, 2018
• Primary Completion: November 12, 2018
• Study Completion: November 12, 2018
• Last Updated: September 10, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)