Impact of Fluid and Passive Leg Raising on Cardiac Output in Patients Undergoing Cardiac Surgery
1 other identifier
observational
20
1 country
1
Brief Summary
Left Ventricular Assist Device (LVAD) implantation is a common surgical procedure in patients with end-stage heart failure. Optimal fluid management is essential for adequate postoperative treatment. It is important to identify which patients will benefit from fluid administration. Passive leg raising (PLR) is a validated dynamic method to predict fluid responsiveness in patients with heart failure by inducing a transient increase in cardiac preload. Objective: To investigate the role of PLR on the management of patients following LVAD implantation in the postoperative period.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for all trials
Started Oct 2016
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 19, 2016
CompletedFirst Submitted
Initial submission to the registry
June 5, 2017
CompletedFirst Posted
Study publicly available on registry
June 7, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2017
CompletedJanuary 18, 2018
June 1, 2017
11 months
June 5, 2017
January 17, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Responsiveness to passive leg raising in patients early after LVAD implantation
Change in LVAD flow due to passive leg raising
5 minutes
Eligibility Criteria
Patients with heart failure candidate for assist device implantation
You may qualify if:
- Patients after VAD implantation
You may not qualify if:
- Age under 18
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Sheba medical center
Ramat Gan, 00000, Israel
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 2 Weeks
- Sponsor Type
- OTHER GOV
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 5, 2017
First Posted
June 7, 2017
Study Start
October 19, 2016
Primary Completion
August 30, 2017
Study Completion
August 30, 2017
Last Updated
January 18, 2018
Record last verified: 2017-06