NCT03172585

Brief Summary

High resolution computed tomography of the chest is the gold standard imaging modality for most pulmonary diseases. However, the associated high expenses, radiation exposure , and its limited possibility for bedside use are a limitation.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2017

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 26, 2017

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 1, 2017

Completed
Same day until next milestone

Study Start

First participant enrolled

June 1, 2017

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2018

Completed
Last Updated

June 1, 2017

Status Verified

May 1, 2017

Enrollment Period

1 year

First QC Date

May 26, 2017

Last Update Submit

May 30, 2017

Conditions

Pleural Diseases

Outcome Measures

Primary Outcomes (1)

  • the number of patients diagnosed with pleural diseases by high resolution computed tomography

    computed tomography on the chest

    30 minutes

Study Arms (1)

High Resolution computed tomography

OTHER

Patients will be included in the study when High resolution chest computed tomography without contrast enhancement is ordered by the primary physician. Before the High resolution chest computed tomography scan, a Trans thoracic ultrasonography will be performed.

Other: High resolution computed tomographyOther: trans thoracic ultrasonography

Interventions

High resolution computed tomographyOTHER

High resolution computed tomography of the chest is the gold standard imaging modality for most pulmonary diseases

High Resolution computed tomography
trans thoracic ultrasonographyOTHER

Trans thoracic ultrasonograghy is used progressively for evaluation of pulmonary diseases . Its non invasive nature , relatively low price ,portability for bedside use, and high reproducible of results allows for incorporation of imaging findings with clinical data

High Resolution computed tomography

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients presenting with dyspnea due to interstitial fibrosis syndrome.
  • pulmonary edema due to any cause.

You may not qualify if:

  • Traumatic lesions
  • Pneumothorax
  • Subcutaneous emphysema
  • Massive pleural effusion with atelectasis, and

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (6)

  • Sartori S, Tombesi P. Emerging roles for transthoracic ultrasonography in pleuropulmonary pathology. World J Radiol. 2010 Feb 28;2(2):83-90. doi: 10.4329/wjr.v2.i2.83.

    PMID: 21160921BACKGROUND

  • Frenz MB, Mee AS. Diagnostic radiation exposure and cancer risk. Gut. 2005 Jun;54(6):889-90. doi: 10.1136/gut.2005.066605. No abstract available.

    PMID: 15888804BACKGROUND

  • Volpicelli G, Mussa A, Garofalo G, Cardinale L, Casoli G, Perotto F, Fava C, Frascisco M. Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome. Am J Emerg Med. 2006 Oct;24(6):689-96. doi: 10.1016/j.ajem.2006.02.013.

    PMID: 16984837BACKGROUND

  • Smargiassi A, Inchingolo R, Soldati G, Copetti R, Marchetti G, Zanforlin A, Giannuzzi R, Testa A, Nardini S, Valente S. The role of chest ultrasonography in the management of respiratory diseases: document II. Multidiscip Respir Med. 2013 Aug 9;8(1):55. doi: 10.1186/2049-6958-8-55.

    PMID: 23937897BACKGROUND

  • Leech M, Bissett B, Kot M, Ntoumenopoulos G. Lung ultrasound for critical care physiotherapists: a narrative review. Physiother Res Int. 2015 Jun;20(2):69-76. doi: 10.1002/pri.1607. Epub 2014 Dec 29.

    PMID: 25545613BACKGROUND

  • Lichtenstein D, Meziere G, Biderman P, Gepner A, Barre O. The comet-tail artifact. An ultrasound sign of alveolar-interstitial syndrome. Am J Respir Crit Care Med. 1997 Nov;156(5):1640-6. doi: 10.1164/ajrccm.156.5.96-07096.

    PMID: 9372688BACKGROUND

MeSH Terms

Conditions

Pleural Diseases

Condition Hierarchy (Ancestors)

Respiratory Tract Diseases

Study Officials

  • Manal Mohamed, MD

    Assiut University

    STUDY DIRECTOR

Central Study Contacts

Gamal Rabeea, MD

CONTACT

00201221729476gamalagmy135@gmail.com

Mohamed Fawzy, MD

CONTACT

00201003032335mohamedadam200010@yahoo.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

May 26, 2017

First Posted

June 1, 2017

Study Start

June 1, 2017

Primary Completion

June 1, 2018

Study Completion

August 1, 2018

Last Updated

June 1, 2017

Record last verified: 2017-05

Data Sharing

IPD Sharing
Will not share