Office Hysteroscopy in Secondary Infertility After Cesarean Section

NCT03166657 | Completed

• 1 other identifier: OHCS
• Study Type: observational
• Target: 56
• Locations: 1 country
• Sites: 1

Brief Summary

All women with history of secondary infertility after caesarean section will be subjected to office hysteroscopy according to Royal college of obstetrics and gynecology guidelines to diagnose any subtle uterine abnormalities not detected by conventional means. Hysteroscopic examination will be done during the proliferation phase of the menstrual cycle. The hysteroscopic evaluation will include assessment of the cervical canal, intrauterine lesions, the endometrium and the uterotubal junction. . If hysteroscopy reveal a lesion, its type, size, location will be recorded. Transvaginal ultrasound will be done after the procedure to detect fluid in the douglas pouch to confirm patent tubes. Asses the uterine scar in details.

Conditions

Infertility, Female

Outcome Measures

Primary Outcomes (1)

• percentage of patients with abnormal scar findings in hysteroscopy

  color of the scar and presence of niche

  1 year

Interventions

office hysteroscopy PROCEDURE

A speculum is first inserted into the vagina. The hysteroscope is then inserted and gently moved through the cervix into uterus. Carbon dioxide gas or a fluid, such as saline will be put through the hysteroscope into uterus to expand it. The gas or fluid helps see the lining more clearly. The amount of fluid used is carefully checked throughout the procedure

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

This study will include all secondary infertile cases after cesarean section who presented to infertility clinic at Women health Hospital, Assiut University

You may qualify if:

• Patients with secondary infertility more than 2 years after cesarean section.
• Normal semen analysis
• Normal hysterosalpingography or laparoscopy within 1year
• Evidence of ovulation by transvaginal ultrasound

You may not qualify if:

• Cases with abnormal semen parameters.
• Patients with abnormal hysterosalpingography.
• Patients with anovulation.
• Hormonal disturbances; high level of prolactin, thyroid hormone disturbances, very high or very low follicular stimulating hormone and luteinizing hormone
• Patients known to be epileptic or with history of fits.
• Cardiac patients ( valve diseases, ischemic, arrhythmic)

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Women Health Hospital

Asyut, 71511, Egypt

Location

Related Publications (2)

• Boivin J, Bunting L, Collins JA, Nygren KG. International estimates of infertility prevalence and treatment-seeking: potential need and demand for infertility medical care. Hum Reprod. 2007 Jun;22(6):1506-12. doi: 10.1093/humrep/dem046. Epub 2007 Mar 21.

  PMID: 17376819 BACKGROUND

• Collins JA, Crosignani PG. Unexplained infertility: a review of diagnosis, prognosis, treatment efficacy and management. Int J Gynaecol Obstet. 1992 Dec;39(4):267-75. doi: 10.1016/0020-7292(92)90257-j.

  PMID: 1361459 BACKGROUND

MeSH Terms

Conditions

Infertility, Female

Condition Hierarchy (Ancestors)

Genital Diseases, Female; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Genital Diseases; Infertility

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Study Record Dates

• First Submitted: May 24, 2017
• First Posted: May 25, 2017
• Study Start: March 1, 2018
• Primary Completion: June 1, 2019
• Study Completion: June 1, 2019
• Last Updated: May 12, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)