Carbon Dioxide Laser and Cryotherapy in Treatment of Warts
Comparative Evaluation of Carbon Dioxide Laser and Cryotherapy by Dermoscopy in Treatment of Viral Wart
1 other identifier
interventional
60
0 countries
N/A
Brief Summary
Viral warts are common skin conditions seen in both children and adults. Human papilloma virus is responsible for verrucae. Cutaneous manifestation of the human papillomavirus, are extremely common particularly on the hands and feet. Warts can induce hard, thickened skin, black pinpoints, pain or tenderness with significant morbidity for the patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Aug 2017
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 23, 2017
CompletedFirst Posted
Study publicly available on registry
May 25, 2017
CompletedStudy Start
First participant enrolled
August 1, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2019
CompletedMay 25, 2017
May 1, 2017
1 year
May 23, 2017
May 23, 2017
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number and size of the lesions.
Dermoscopic evaluation
Two months
Study Arms (2)
Carbon dioxide laser group
EXPERIMENTAL(group A): thirty patients will be treated by application of carbon dioxide laser.
Cryotherapy group
ACTIVE COMPARATOR(group B): thirty patients will be treated by cryotherapy application.
Interventions
Eligibility Criteria
You may qualify if:
- Patients with common warts male or females any age.
- Patient is able to read and understand English and will give written informed consent to participate.
- Patient elects to undergo carbon dioxide laser therapy or cryotherapy for treatment of common warts.
- Warts to be treated will be located only on the hands.
You may not qualify if:
- Non cooperative patients.
- Patients on other lines of treatment.
- Pregnant and lactating females.
- Patients receiving topical treatment in the previous two weeks.
- Secondary infection.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (4)
Vlahovic TC, Khan MT. The Human Papillomavirus and Its Role in Plantar Warts: A Comprehensive Review of Diagnosis and Management. Clin Podiatr Med Surg. 2016 Jul;33(3):337-53. doi: 10.1016/j.cpm.2016.02.003. Epub 2016 Mar 29.
PMID: 27215155RESULTKwok CS, Gibbs S, Bennett C, Holland R, Abbott R. Topical treatments for cutaneous warts. Cochrane Database Syst Rev. 2012 Sep 12;2012(9):CD001781. doi: 10.1002/14651858.CD001781.pub3.
PMID: 22972052RESULTAndrews MD. Cryosurgery for common skin conditions. Am Fam Physician. 2004 May 15;69(10):2365-72.
PMID: 15168956RESULTZalaudek I, Giacomel J, Cabo H, Di Stefani A, Ferrara G, Hofmann-Wellenhof R, Malvehy J, Puig S, Stolz W, Argenziano G. Entodermoscopy: a new tool for diagnosing skin infections and infestations. Dermatology. 2008;216(1):14-23. doi: 10.1159/000109353.
PMID: 18032894RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 23, 2017
First Posted
May 25, 2017
Study Start
August 1, 2017
Primary Completion
August 1, 2018
Study Completion
August 1, 2019
Last Updated
May 25, 2017
Record last verified: 2017-05
Data Sharing
- IPD Sharing
- Will not share