Quality of Life in Patients With Chronic Urticaria

NCT03163875 | Unknown

• 1 other identifier: ziad
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

Urticaria is one of the most frequent presenting complaints in dermatology, allergy, and emergency departments. The term chronic urticaria (CU) is understood as the appearance of recurrent wheals more than twice a week for over 6 consecutive weeks .Urticaria is not a single disease but a reaction pattern that represents cutaneous mast cell degranulation, resulting in extravasation of plasma into the dermis. The incidence of chronic urticaria is unknown, but it is thought to occur in 0.1%-3% of the population

Conditions

Chronic Urticaria

Keywords

erythema; wheal formation; vascular reaction of the skin

Outcome Measures

Primary Outcomes (1)

• measure number of patients affected with depression and anxity

  The levels of depression and anxiety will be assessed by Hospital Anxiety Depression Scale (HADS) .

  one year

Interventions

Hospital Anxiety and Depression Scale OTHER

To assess the levels of depression and anxiety, quality of sleep and quality of life (QoL) in chronic urticaria patients, using an interdisciplinary approach combining interview/questionnaire-based psychiatric and dermatological evaluations

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Antihistamines will be discontinued at least 72 h prior to evaluation.

You may qualify if:

• Patients with chronic urticaria defined as a 6-week or longer history of daily or almost daily itchy cutaneous weals with individual lesions lasting less than 24 h.
• Age between 18 and 60 years.

You may not qualify if:

• Patients who are unable to understand the questions, are unwilling to complete the questionnaire, or who have a psychiatric disorder, or obstructive sleep apnea.
• Patients with malignant or central nervous system disease. Patients with cognitive impairment due to a current cerebral or psychotic illness.
• Patients with current psychotherapy . glucocorticoids therapy in the last month.

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Chronic Urticaria; Erythema

Interventions

4-amino-4'-hydroxylaminodiphenylsulfone

Condition Hierarchy (Ancestors)

Urticaria; Skin Diseases, Vascular; Skin Diseases; Skin and Connective Tissue Diseases; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Skin Manifestations; Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator

Study Record Dates

• First Submitted: May 15, 2017
• First Posted: May 23, 2017
• Study Start: June 1, 2017
• Primary Completion: June 10, 2018
• Study Completion: August 1, 2018
• Last Updated: May 30, 2017

Record last verified: 2017-05

Data Sharing

• IPD Sharing: Will not share